Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SIK1 | P57059 | 1/20 | 0.48 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.48 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127023 | 0.81 | PRKDC (0.57) | PRKDCMAPTALDH1A1HTTKDM4E | |
| SCHEMBL8081309 | 0.80 | OXTR (0.55) | PRKDCMAPTSIK1SIK2SIK3 | |
| SCHEMBL8081342 | 0.80 | OXTR (0.53) | MAPTSIK1SIK2SIK3ALDH1A1 | |
| SCHEMBL1240530 | 0.75 | PRKDC (0.71) | PRKDCMAPTALDH1A1HTTKDM4E | |
| SCHEMBL14339148 | 0.74 | PRKDC (0.73) | PRKDCMAPTALDH1A1HTTKDM4E | |
| SCHEMBL7345338 | 0.74 | ALDH1A1 (0.49) | MAPTALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL29776854 | 0.74 | PRKDC (1.00) | PRKDCMAPTALDH1A1HTTKDM4E | |
| SCHEMBL600210 | 0.74 | PRKDC (1.00) | PRKDCMAPTALDH1A1HTTKDM4E | |
| SCHEMBL7336830 | 0.73 | NOTUM (0.44) | ALDH1A1KDM4EMAPK9MAPK10 | |
| SCHEMBL6643194 | 0.72 | PRKDC (0.67) | PRKDCMAPTALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |