Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.73 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | FPR2 | P25090 | 4/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19234762 | 0.91 | SAE1 (0.69) | SAE1UBA2ABCG2SMN1; SMN2RAB9A | |
| SCHEMBL15093809 | 0.88 | HRH3 (0.65) | SAE1UBA2ABCG2RAB9ANPC1 | |
| SCHEMBL8866830 | 0.87 | SAE1 (0.73) | SAE1UBA2ABCG2SMN1; SMN2RAB9A | |
| SCHEMBL8866824 | 0.87 | SAE1 (0.73) | SAE1UBA2ABCG2SMN1; SMN2RAB9A | |
| SCHEMBL4121995 | 0.87 | SAE1 (0.78) | SAE1UBA2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4117832 | 0.86 | MAPT (0.69) | ABCG2SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL4110520 | 0.86 | MAPT (0.80) | ABCG2SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL11092496 | 0.84 | RAB9A (1.00) | SAE1UBA2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14462302 | 0.83 | SAE1 (0.78) | SAE1UBA2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4106216 | 0.83 | RAB9A (0.67) | ABCG2SMN1; SMN2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | SAE1 2238/4885UBA2 318/4885ABCG2 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.