SCHEMBL4127901

SCHEMBL4127901

[CH2]N(CCCCC)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.50
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.44
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
LMNA P02545 2/20 0.38
GBA1 P04062 1/20 0.36
SLC22A1 O15245 2/20 0.35
SLC22A2 O15244 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGLL Q99685 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405732 0.97 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL4395109 0.97 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL15899616 0.97 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL4391178 0.97 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL7646024 0.97 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL11071352 0.97 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL11125895 0.94 DNM1 (0.52) DNM1TSHRTHRBCA12CA1
SCHEMBL11124727 0.94 DNM1 (0.46) DNM1TSHRTHRBCA12CA1
SCHEMBL7283453 0.91 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL78616 0.90 TSHR (0.40) DNM1TSHRTHRBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9725589-B2 Method of preparing acrylic polymers and products produced thereby LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-08-08 US claimed
US-20140336343-A1 Method Of Preparing Acrylic Polymers And Products Produced Thereby LUBRIZOL ADVANCED MATERIALS, INC. 2014-11-13 US claimed
EP-2794672-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY Lubrizol Advanced Materials, Inc. (US) 2014-10-29 EP claimed
WO-2013096206-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-06-27 WO claimed
EP-0222839-A4 ANTIMALARIAL COMPOUNDS. UNIV AUSTRALIAN (AU) 1988-11-09 EP claimed
EP-0222839-A1 ANTIMALARIAL COMPOUNDS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1987-05-27 EP claimed
WO-1986006718-A1 ANTIMALARIAL COMPOUNDS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1986-11-20 WO claimed
US-11975002-B2 Preparation and composition for treatment of malignant tumors TAIHO PHARMACEUTICAL CO., LTD. (JP) 2024-05-07 US disclosed
US-11883404-B2 Preparation and composition for treatment of malignant tumors TAIHO PHARMACEUTICALS CO., LTD. (JP) 2024-01-30 US disclosed
EP-3864002-B1 ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-27 EP disclosed
US-11690843-B2 2023-07-04 US disclosed
US-20220033345-A1 ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2022-02-03 US disclosed
EP-3864002-A1 ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS 3M Innovative Properties Company (US) 2021-08-18 EP disclosed
EP-0222839-A4 ANTIMALARIAL COMPOUNDS. UNIV AUSTRALIAN (AU) 1988-11-09 EP disclosed
EP-0236140-A2 Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-09 EP disclosed
EP-0222839-A1 ANTIMALARIAL COMPOUNDS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1987-05-27 EP disclosed
EP-0215435-A1 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-03-25 EP disclosed
WO-1986006718-A1 ANTIMALARIAL COMPOUNDS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1986-11-20 WO disclosed
EP-0052016-B1 CARBOSTYRIL COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-09-05 EP disclosed
US-4414390-A CARDIOTONIC AGENTS OTSUKA, PHARMACEUTICAL CO., LTD. (JP) 1983-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11690843-B2 FGFR3, FGFR1, FGFR4 DNM1 1637/4885TSHR 3877/4885THRB 2400/4885
US-11975002-B2 Preparation and composition for treatment of malignant tumors FGFR3, FGFR1, FGFR4 DNM1 996/4885TSHR 3712/4885THRB 2406/4885
US-11883404-B2 Preparation and composition for treatment of malignant tumors FGFR3, FGFR1, FGFR4 DNM1 996/4885TSHR 3712/4885THRB 2406/4885
US-20220033345-A1 ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS PARP1, ETFA, PARP2 DNM1 414/4885TSHR 3927/4885THRB 4166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.