SCHEMBL4127927

SCHEMBL4127927

O=Cc1ccccc1N(C=O)C=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
THRB P10828 1/20 0.55
BLM P54132 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 5/20 0.44
TRIM24 O15164 2/20 0.44
TRIM33 Q9UPN9 2/20 0.44
TSHR P16473 1/20 0.44
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.38
ERN1 O75460 2/20 0.37
SRC P12931 1/20 0.35
CYP2A6 P11509 3/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.33
IMPDH2 P12268 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20139129 0.82 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL374886 0.80 LMNA (0.60) LMNAKMT2AMEN1THRBBLM
SCHEMBL28042286 0.77 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL12651732 0.77 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL29954357 0.76 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL97297 0.76 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL20471914 0.76 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
Hydrochloric Acid SCHEMBL11758316 0.74 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL12651735 0.74 LMNA (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL29354732 0.73 KMT2A (0.50) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5552297-A ANALYZING FOR LEAD IN BODY FLUIDS, BLOOD, REACTION OF AMINOLEVULINIC ACID TO FORM PORPHOBILINOGEN, COLORIMETRIC ABBOTT LABORATORIES (US) 1996-09-03 US claimed
US-20120322998-A1 Gallium Phthalocyanine Crystal, Production Process Thereof, Photoreceptor, Process Cartridge and Image Forming Apparatus FUJI XEROX CO., LTD. (JP) 2012-12-20 US disclosed
US-20090068576-A1 Gallium phthalocyanine crystal, production process thereof, photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2009-03-12 US disclosed