Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.42 |
| ▸ | CASP6 | P55212 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | AOC2 | O75106 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127965 | 1.00 | CTDSP1 (0.42) | CTDSP1CASP6NSD2POLBGRK2 | |
| SCHEMBL4134807 | 0.79 | NR1H4 (0.50) | FFAR1NR1H4PDE4BPDE4D | |
| SCHEMBL4134811 | 0.79 | NR1H4 (0.50) | FFAR1NR1H4PDE4BPDE4D | |
| SCHEMBL4138121 | 0.78 | NSD2 (0.43) | CTDSP1CASP6NSD2POLBGRK2 | |
| SCHEMBL4138118 | 0.78 | NSD2 (0.43) | CTDSP1CASP6NSD2POLBGRK2 | |
| SCHEMBL4635128 | 0.77 | POLB (0.42) | CTDSP1CASP6NSD2POLBGRK2 | |
| SCHEMBL4120873 | 0.76 | PTGS1 (0.48) | POLBL3MBTL1MEN1KMT2ANR1H4 | |
| SCHEMBL4120866 | 0.76 | PTGS1 (0.48) | POLBL3MBTL1MEN1KMT2ANR1H4 | |
| SCHEMBL4132534 | 0.73 | PDE4B (0.42) | MEN1KMT2ATP53PDE4BPDE4D | |
| SCHEMBL4132544 | 0.73 | PDE4B (0.42) | MEN1KMT2ATP53PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | claimed |
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | PTPRF, PTPA, PTPRJ | CTDSP1 3470/4885CASP6 2156/4885NSD2 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.