Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | AOC2 | O75106 | 3/20 | 0.39 |
| ▸ | DUSP22 | Q9NRW4 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138118 | 0.86 | NSD2 (0.43) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4138121 | 0.86 | NSD2 (0.43) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4123871 | 0.81 | POLB (0.51) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4123875 | 0.81 | POLB (0.51) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4634791 | 0.80 | FFAR1 (0.47) | PDE4BPDE4DFFAR1 | |
| SCHEMBL4127967 | 0.77 | CTDSP1 (0.42) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4127965 | 0.77 | CTDSP1 (0.42) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4121787 | 0.76 | NSD2 (0.37) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4121784 | 0.76 | NSD2 (0.37) | POLBNSD2CTDSP1GRK2CASP6 | |
| SCHEMBL4129359 | 0.75 | MAPT (0.41) | POLBNSD2CTDSP1GRK2DUSP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |