SCHEMBL4128580

SCHEMBL4128580

Oc1ccc(C2(c3ccc(OCC4CO4)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
ALDH1A1 P00352 5/20 0.43
TP53 P04637 4/20 0.43
TSHR P16473 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HIF1A Q16665 2/20 0.43
CYP3A4 P08684 2/20 0.43
MAPT P10636 5/20 0.43
LMNA P02545 3/20 0.43
HPGD P15428 2/20 0.43
PKM P14618 2/20 0.43
CYP1A2 P05177 1/20 0.43
PPARG P37231 1/20 0.43
GAA P10253 1/20 0.43
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
KDM4E B2RXH2 1/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157321 0.93 TDP1 (0.58) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL29386530 0.93 TDP1 (0.58) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL30044297 0.93 TDP1 (0.58) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL13827403 0.93 TDP1 (0.58) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL15700021 0.93 TDP1 (0.58) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL20411194 0.91 TDP1 (0.59) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL15966166 0.90 TDP1 (0.54) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL27895119 0.89 TDP1 (0.50) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL1457444 0.88 ESR1 (0.42) TDP1MEN1KMT2AALDH1A1TP53
SCHEMBL23153041 0.87 TDP1 (0.51) TDP1MEN1KMT2AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102727470-B Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer UNIV BEIJING 2014-02-19 CN disclosed
CN-102727470-A Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer UNIV BEIJING 2012-10-17 CN disclosed
US-20090182079-A1 Carbon Black Surface-Modified with Benzene Compound and Carbon Black Dispersion Composition for Black Matrix Using the Same CHEIL INDUSTRIES INC. (KR) 2009-07-16 US disclosed
US-7361432-B2 Composition for hologram-recording material, hologram-recording medium, and process for producing the same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-04-22 US disclosed
US-20070101903-A1 Carbon black surface-modified with benzene compound and carbon black dispersion composition for black matrix using the same CHEIL INDUSTRIES, INC. (KR) 2007-05-10 US disclosed
US-20040096776-A1 Composition for hologram-recording material, hologram-recording medium, and process for producing the same Daiso, Co., Ltd. (JP) 2004-05-20 US disclosed
EP-1376268-A1 COMPOSITION FOR HOLOGRAM-RECORDING MATERIAL, HOLOGRAM-RECORDING MEDIUM, AND PROCESS FOR PRODUCING THE SAME National Institute of Advanced Industrial Science and Technology (JP) 2004-01-02 EP disclosed
US-20030096172-A1 Hologram recording material composition and hologram recording medium DAISO CO., LTD. (JP) 2003-05-22 US disclosed