⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814132 | 0.79 | — | — | |
| SCHEMBL640316 | 0.79 | — | — | |
| SCHEMBL5385812 | 0.79 | — | — | |
| SCHEMBL7627830 | 0.79 | — | — | |
| SCHEMBL2782669 | 0.79 | — | — | |
| SCHEMBL7934102 | 0.77 | TDP1 (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL8428638 | 0.77 | TDP1 (0.55) | — | |
| Ammonia Solution, Strong SCHEMBL11366639 | 0.77 | TDP1 (0.55) | — | |
| Hydrochloric Acid SCHEMBL9622278 | 0.77 | TDP1 (0.48) | — | |
| SCHEMBL5983734 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |