Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8428638

N.N.O=C(O)CC(Cl)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.43
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
FOLH1 Q04609 3/20 0.39
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.37
GABRR1 P24046 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11366639 1.00 TDP1 (0.55) TDP1SMN1; SMN2SLC22A6LMNATSHR
SCHEMBL640316 0.97
SCHEMBL2782669 0.97
SCHEMBL7814132 0.97
SCHEMBL7934102 0.94 TDP1 (0.48) TDP1SMN1; SMN2SLC22A6LMNATSHR
Hydrochloric Acid SCHEMBL9622278 0.94 TDP1 (0.48) TDP1SMN1; SMN2SLC22A6LMNATSHR
Fumaric Acid SCHEMBL3399221 0.85 TSHR (0.43) TDP1SMN1; SMN2SLC22A6LMNATSHR
Maleic Acid SCHEMBL3399215 0.85 TSHR (0.43) TDP1SMN1; SMN2SLC22A6LMNATSHR
SCHEMBL4128955 0.77
SCHEMBL5983734 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36234-E Aspartic acid copolymers and their preparation DONLAR CORPORATION (US) 1999-06-22 US claimed
US-RE36234-E Aspartic acid copolymers and their preparation DONLAR CORPORATION (US) 1999-06-22 US disclosed
US-5478919-A Condensation polymerization of aspartic acid precursors and amino, hydroxy or carboxy-functional monomers to form polysuccinimide copolymer; hydrolysis to aspartic acid copolymer DONLAR CORPORATION (US) 1995-12-26 US disclosed