⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056907 | 0.95 | — | — | |
| SCHEMBL9059055 | 0.88 | — | — | |
| SCHEMBL9040776 | 0.84 | — | — | |
| SCHEMBL9041926 | 0.84 | — | — | |
| SCHEMBL9056001 | 0.83 | — | — | |
| SCHEMBL9057804 | 0.82 | AGTR1 (0.51) | — | |
| SCHEMBL8695272 | 0.81 | — | — | |
| SCHEMBL9043827 | 0.79 | AGTR1 (0.68) | — | |
| SCHEMBL9041141 | 0.79 | — | — | |
| SCHEMBL3265203 | 0.78 | AGTR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | claimed |
| US-10149909-B2 | Fortifier | TORAY INDUSTRIES, INC. (JP) | 2018-12-11 | — | — | US | disclosed |
| US-20170080089-A1 | FORTIFIER | TORAY INDUSTRIES, INC. (JP) | 2017-03-23 | — | — | US | disclosed |
| US-9546145-B2 | Combination therapy for the treatment of chronic renal failure with an angiotensin II receptor antagonist and beraprost | TORAY INDUSTRIES, INC. (JP) | 2017-01-17 | — | — | US | disclosed |
| US-20090176848-A1 | FORTIFIER | TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) | 2009-07-09 | — | — | US | disclosed |
| US-20060217421-A1 | Fortifier | TORAY INDUSTRIES, INC. (JP) | 2006-09-28 | — | — | US | disclosed |