Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.85 |
| ▸ | GAA | P10253 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.85 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.67 |
| ▸ | TUBB | P07437 | 2/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.67 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.67 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.67 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558901 | 1.00 | MAPT (0.85) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL27783737 | 0.93 | MAPT (0.73) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL30435437 | 0.92 | MAPT (1.00) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL8049833 | 0.92 | MAPT (0.71) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL27887101 | 0.92 | MAPT (1.00) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| Calycopterin SCHEMBL2214965 | 0.89 | KDM4E (0.73) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL27881183 | 0.89 | MAPT (0.67) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL31051345 | 0.89 | KDM4E (0.67) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL28801813 | 0.89 | MAPT (0.67) | MAPTKDM4EGAAALDH1A1TUBB4A | |
| SCHEMBL1764663 | 0.88 | ABCG2 (0.66) | MAPTKDM4EGAAALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010194-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | Rutgers, The State University of New Jersey (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |
| CN-118050448-A | Component analysis and application of wide-stalked flavone before and after stir-frying | 吉林化工学院 | 2024-05-17 | — | — | CN | disclosed |
| EP-1928480-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | Wellgen, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007024982-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | WELLGEN, INC. (US) | 2007-03-01 | — | — | WO | disclosed |