⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213307 | 0.84 | — | — | |
| SCHEMBL11021303 | 0.82 | LMNA (0.37) | — | |
| SCHEMBL651599 | 0.77 | — | — | |
| SCHEMBL649617 | 0.77 | — | — | |
| SCHEMBL8065640 | 0.76 | — | — | |
| SCHEMBL11211511 | 0.76 | LMNA (0.41) | — | |
| SCHEMBL669602 | 0.74 | — | — | |
| SCHEMBL20641609 | 0.74 | — | — | |
| SCHEMBL15160836 | 0.74 | LMNA (0.32) | — | |
| SCHEMBL441399 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101408-B2 | Disperse dye mixtures | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2006-09-05 | — | — | US | claimed |
| US-20040226112-A1 | Disperse dye mixtures | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2004-11-18 | — | — | US | claimed |
| EP-1477531-A1 | Disperse dye mixtures | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2004-11-17 | — | — | EP | claimed |
| US-20090143375-A1 | Tricyclic Lactam Derivatives, Their Manufacture and Use as Pharmaceutical Agents | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-04 | — | — | US | disclosed |
| US-7462639-B2 | e.g 3-(7,7-Dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-1H-pyrazol-4-yl]-carbamic acid benzyl ester; Aurora A (serotonin/threonine) kinase inhibitors; anticarcinogenic agent; colorectal, breast, lung, prostate, pancreatic, gastric, bladder, ovarian cancer, melanoma, neuroblastoma | HOFFMANN-LA ROCHE INC. (US) | 2008-12-09 | — | — | US | disclosed |
| EP-1885725-B1 | TRICYCLIC AZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-09-24 | — | — | EP | disclosed |
| EP-1966213-A1 | TRICYCLIC LACTAM DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| EP-1885725-A1 | TRICYCLIC AZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-02-13 | — | — | EP | disclosed |
| EP-1879894-A1 | AMINOPYRAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-01-23 | — | — | EP | disclosed |
| CN-100360617-C | Disperse dye mixtures | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2008-01-09 | — | — | CN | disclosed |
| WO-2007068465-A1 | TRICYCLIC LACTAM DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-21 | — | — | WO | disclosed |
| US-5486609-A | AMINATION OF HALOPHENOLS WITH PRIMARY AND SECONDARY AMINES | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |
| EP-0689575-A1 | ANTHRAQUINONES AS MARKING AGENTS FOR MINERAL OILS | BASF AG (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0673919-A1 | Process for the preparation of carbocylic m-amino-hydroxyaromatic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0669968-A1 | ANILINES AS MARKING AGENTS FOR MINERAL OILS. | BASF AG (DE) | 1995-09-06 | — | — | EP | disclosed |
| WO-1995007460-A1 | METHOD OF DETECTING NAPHTHYLAMINES IN MINERAL OILS | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-16 | — | — | WO | disclosed |
| WO-1994021752-A1 | ANTHRAQUINONES AS MARKING AGENTS FOR MINERAL OILS | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-29 | — | — | WO | disclosed |
| CN-1092098-A | Aniline as markers for mineral oils | BASF AG (DE) | 1994-09-14 | — | — | CN | disclosed |
| WO-1994011466-A1 | ANILINES AS MARKING AGENTS FOR MINERAL OILS | BASF AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |