Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878131 | 0.96 | SSTR5 (0.62) | SSTR5KCNH2SSTR1 | |
| SCHEMBL1874534 | 0.91 | SSTR5 (0.58) | SSTR5KCNH2 | |
| SCHEMBL27779798 | 0.86 | SSTR5 (0.53) | SSTR5KCNH2 | |
| SCHEMBL4129632 | 0.83 | SSTR5 (0.63) | SSTR5KCNH2 | |
| SCHEMBL4125485 | 0.83 | SSTR5 (0.65) | SSTR5KCNH2 | |
| SCHEMBL1877058 | 0.82 | SSTR5 (0.59) | SSTR5 | |
| SCHEMBL1874576 | 0.81 | SSTR5 (0.46) | SSTR5SSTR1 | |
| SCHEMBL1878382 | 0.81 | SSTR5 (0.58) | SSTR5KCNH2SSTR1 | |
| SCHEMBL1877959 | 0.81 | SSTR5 (0.53) | SSTR5SSTR1 | |
| SCHEMBL1877373 | 0.81 | SSTR5 (0.63) | SSTR5KCNH2SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066658-A1 | PYRIDINE- AND QUINOLINE-PYRIMIDINE-DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008031735-A1 | PYRIDINE- AND QUINOLINE-PYRIMIDINE-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-20 | — | — | WO | disclosed |