Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.55 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.54 |
| ▸ | IL6 | P05231 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136376 | 0.94 | TLR7 (0.64) | TLR7NUDT1IL6 | |
| SCHEMBL4141253 | 0.88 | TLR7 (0.63) | TLR7NUDT1IL6 | |
| SCHEMBL4152802 | 0.83 | TLR7 (0.54) | TLR7NUDT1IL6 | |
| SCHEMBL4131435 | 0.82 | TLR7 (0.61) | TLR7NUDT1IL6 | |
| SCHEMBL4136692 | 0.81 | TLR7 (0.74) | TLR7NUDT1IL6 | |
| SCHEMBL4140375 | 0.81 | TLR7 (0.63) | TLR7IL6 | |
| SCHEMBL4130847 | 0.80 | TLR7 (0.60) | TLR7IL6 | |
| SCHEMBL4149250 | 0.80 | TLR7 (0.61) | TLR7IL6 | |
| SCHEMBL4590781 | 0.79 | TLR7 (0.51) | TLR7NUDT1 | |
| SCHEMBL13850470 | 0.78 | TLR7 (0.63) | TLR7NUDT1IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118263-A1 | Novel Adenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1939202-A1 | NOVEL ADENINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118263-A1 | Novel Adenine Compound | ADORA1, ADORA2A, ADORA3 | TLR7 389/4885NUDT1 7/4885IL6 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.