⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27670460 | 0.87 | NAPRT (0.55) | — | |
| 2-Methoxyethanol SCHEMBL28562105 | 0.83 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL222027 | 0.81 | SMN1; SMN2 (0.68) | — | |
| SCHEMBL13134159 | 0.79 | RXFP1 (0.51) | — | |
| SCHEMBL3280929 | 0.79 | — | — | |
| SCHEMBL27633440 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL28938372 | 0.78 | HPGD (0.42) | — | |
| SCHEMBL8847816 | 0.77 | — | — | |
| SCHEMBL568862 | 0.77 | — | — | |
| SCHEMBL15381286 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| CN-114761423-A | Methods and compositions for tissue regeneration | 中国科学院动物研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-114286859-A | Engineered myogenic cell compositions and uses thereof | 中国科学院动物研究所 | 2022-04-05 | — | — | CN | disclosed |
| EP-3774815-A1 | THIENOPYRIMIDINONE COMPOUNDS | Biotheryx Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019191451-A1 | THIENOPYRIMIDINONE COMPOUNDS | BIOTHERYX, INC. (US) | 2019-10-03 | — | — | WO | disclosed |
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-9840515-B2 | Protein kinase D inhibitors | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-12-12 | — | — | US | disclosed |
| EP-0177923-A1 | Tetrazolothienopyridines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0177924-A1 | (Tetrazolyl)Thienopyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0177065-A1 | Thienotriazines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-09 | — | — | EP | disclosed |
| US-4581455-A | Tetrazolothienopyridines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4581448-A | Thienotriazines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4540786-A | Preparation of 2-chloro-3-cyano-quinolines | THE DOW CHEMICAL COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
| US-4375544-A | Fused pyridines | CRODA SYNTHETIC CHEMICALS LIMITED (GB) | 1983-03-01 | — | — | US | disclosed |
| EP-0003645-B1 | PROCESS FOR THE PREPARATION OF AROMATIC (B)-FUSED PYRIDINES AND NOVEL THIENO(B)PYRIDINES | CRODA SYNTHETIC CHEMICALS LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |
| EP-0003645-A1 | Process for the preparation of aromatic (b)-fused pyridines and novel thieno(b)pyridines | CRODA SYNTHETIC CHEMICALS LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |
| WO-1979000540-A1 | HETEROCYCLIC COMPOUNDS | CRODA SYNTHETIC CHEM LTD (GB) | 1979-08-09 | — | — | WO | disclosed |