Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | BPTF | Q12830 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134826 | 0.83 | ADORA1 (0.74) | ADORA1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL13739529 | 0.83 | ADORA1 (0.78) | ADORA1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL6997953 | 0.82 | ADORA1 (0.73) | ADORA1KDM4EMAPTBPTFALDH1A1 | |
| SCHEMBL10856568 | 0.81 | ADORA1 (0.69) | ADORA1KDM4EMAPTBPTFALDH1A1 | |
| SCHEMBL938054 | 0.80 | ADORA1 (1.00) | ADORA1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL351992 | 0.80 | ADORA1 (0.82) | ADORA1KDM4EMAPTBPTFALDH1A1 | |
| SCHEMBL3499018 | 0.80 | ADORA1 (1.00) | ADORA1KDM4EMAPTBPTFALDH1A1 | |
| SCHEMBL4151112 | 0.78 | ALDH1A1 (0.57) | ADORA1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL2489856 | 0.77 | ALDH1A1 (0.65) | ADORA1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL10711946 | 0.77 | ALDH1A1 (0.62) | ADORA1KDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | claimed |
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | disclosed |
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | TP53, BRDT, VHL | ADORA1 4169/4885KDM4E 2942/4885MAPT 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.