Biphenyl

Biphenyl

SCHEMBL4132218

O=C(O)CCC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.71
LMNA P02545 3/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
CYP1A2 P05177 2/20 0.71
RAB9A P51151 1/20 0.71
HIF1A Q16665 1/20 0.71
NR4A2 P43354 1/20 0.61
GAA P10253 2/20 0.58
TSHR P16473 2/20 0.58
ABCC4 O15439 1/20 0.58
PTGS1 P23219 1/20 0.58
HTT P42858 1/20 0.58
KEAP1 Q14145 1/20 0.56
ALDH1A1 P00352 4/20 0.54
CYP2C19 P33261 2/20 0.54
ALKBH5 Q6P6C2 1/20 0.53
SUCNR1 Q9BXA5 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
HDAC3 O15379 1/20 0.52
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27929406 0.89 FFAR1 (0.61) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Adipic Acid SCHEMBL248245 0.89 FFAR1 (0.61) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Glutarate SCHEMBL250428 0.89 FFAR1 (0.61) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Biphenyl SCHEMBL11768612 0.89 FFAR1 (0.61) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Biphenyl SCHEMBL29081077 0.87 FFAR1 (0.59) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Biphenyl SCHEMBL7642659 0.87 HDAC3 (0.65) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Octanedioate SCHEMBL8026045 0.87 HDAC3 (0.65) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Sebacic Acid SCHEMBL3165598 0.87 HDAC3 (0.65) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Biphenyl SCHEMBL3175348 0.87 HDAC3 (0.65) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Biphenyl SCHEMBL27826000 0.86 FFAR1 (0.57) FFAR1LMNASMN1; SMN2CYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4349881-B1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF NINGBO INSTITUTE OF MATERIALS TECH & ENGINEERING CHINESE ACADEMY OF SCIENCES (CN) 2026-04-29 EP claimed
EP-4349881-A1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences (CN) 2024-04-10 EP claimed
CN-1066766-C Diketopyrrolopyrrole pigment with high chroma CIBA SC HOLDING AG (CH) 2001-06-06 CN claimed
EP-4349881-B1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF NINGBO INSTITUTE OF MATERIALS TECH & ENGINEERING CHINESE ACADEMY OF SCIENCES (CN) 2026-04-29 EP disclosed
EP-4349881-A1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences (CN) 2024-04-10 EP disclosed
CN-113281925-A Light control film and display panel 深圳市华星光电半导体显示技术有限公司 2021-08-20 CN disclosed
CN-103402975-A Beta-hydroxyalkylamide and resin composition TOYO INK SC HOLDINGS CO LTD 2013-11-20 CN disclosed
CN-101374914-B Alpha-diketopyrrolopyrrole pigment, coloring composition using same, and red-colored film TOYO INK MFG CO 2013-08-14 CN disclosed
CN-101273083-B Method for improving the flowability of polymer melts CIBA HOLDING INC 2012-04-18 CN disclosed
CN-1553913-B Process for the direct preparation of pyrrolo [3,4-c]pyrroles CIBA SC HOLDING AG 2011-10-05 CN disclosed
CN-101189295-B Cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO INC 2010-12-15 CN disclosed
WO-2007011006-A1 OPTICALLY ANISOTROPIC FILM, POLARIZING FILM, PRODUCING PROCESS THEREOF, AND APPLICATION USE THEREOF FUJI FILM CORPORATION (JP) 2007-01-25 WO disclosed
CN-1250615-C Polypropylene resin moldings and process for production thereof NEW JAPAN CHEM CO LTD (JP) 2006-04-12 CN disclosed
CN-1555394-A Polypropylene resin moldings and process for production thereof �ձ�������ʽ���� 2004-12-15 CN disclosed
CN-1553913-A Process for the direct preparation of pyrrolo [3,4-c]pyrroles �������⻯ѧƷ�ع����޹�˾ 2004-12-08 CN disclosed
CN-1525907-A Continuous biaxial stretching polypropylene porous membrane and preparation method thereof �ձ�������ʽ���� 2004-09-01 CN disclosed
CN-1119364-C Propylene ethylene copolymer compositions and process for the production thereof CHISSO CORP (JP) 2003-08-27 CN disclosed
CN-1066766-C Diketopyrrolopyrrole pigment with high chroma CIBA SC HOLDING AG (CH) 2001-06-06 CN disclosed
CN-1169743-A Propylene-ethylene copolymer composition and process for producing the same CHISSO CORP (JP) 1998-01-07 CN disclosed
CN-1113251-A Diketopyrrolopyrrole pigment with high chroma CIBA GEIGY AG (CH) 1995-12-13 CN disclosed