Octanedioate

Octanedioate

SCHEMBL8026045

O=C(O)CCCCCCC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.65
HDAC4 P56524 2/20 0.65
HDAC1 Q13547 2/20 0.65
HDAC7 Q8WUI4 2/20 0.65
HDAC2 Q92769 2/20 0.65
HDAC10 Q969S8 2/20 0.65
HDAC11 Q96DB2 2/20 0.65
HDAC8 Q9BY41 2/20 0.65
HDAC6 Q9UBN7 2/20 0.65
HDAC9 Q9UKV0 2/20 0.65
HDAC5 Q9UQL6 2/20 0.65
MAPT P10636 2/20 0.65
RXFP1 Q9HBX9 1/20 0.65
LMNA P02545 5/20 0.60
TSHR P16473 2/20 0.60
NFKB1 P19838 1/20 0.60
PMP22 Q01453 1/20 0.60
FFAR1 O14842 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
MAPK1 P28482 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7642659 1.00 HDAC3 (0.65) HDAC3HDAC4HDAC1HDAC7HDAC2
Sebacic Acid SCHEMBL3165598 1.00 HDAC3 (0.65) HDAC3HDAC4HDAC1HDAC7HDAC2
Biphenyl SCHEMBL3175348 1.00 HDAC3 (0.65) HDAC3HDAC4HDAC1HDAC7HDAC2
Adipic Acid SCHEMBL248245 0.97 FFAR1 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Biphenyl SCHEMBL11768612 0.97 FFAR1 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Sebacic Acid SCHEMBL27729682 0.95 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Biphenyl SCHEMBL27929406 0.92 FFAR1 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Glutarate SCHEMBL250428 0.92 FFAR1 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Stearic Acid SCHEMBL8855788 0.89 GPR84 (0.68) HDAC11MAPTTSHRFFAR1TDP1
Stearic Acid SCHEMBL29634243 0.89 GPR84 (0.68) HDAC11MAPTTSHRFFAR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013420-A ALKALINE TREATMENT BATCH PROCESSING FOR SILVER HALIDE EMULSION MULTILAYER DEVELOPMENT AGFA-GEVAERT AG (DE) 2000-01-11 US disclosed
EP-0618503-B1 Image forming method including heat development while covering surface of light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-05-19 EP disclosed
US-5714303-A COMPRISING A SUPPORT, A STRIPPABLE LAYER CONTAINING A FLUORINE-CONTAINING SURFACTANT AND A PHOTOSENSITIVE LAYER OF SILVER HALIDE, REDUCING AGENT AND AN UNSATURATED POLYMERIZABLE COMPOUND OR POLYMER; RESOLUTION FUJI PHOTO FILM CO., LTD. (JP) 1998-02-03 US disclosed
US-5612167-A Image forming method using strippable layer and light-sensitive polymerizable layer containing silver halide FUJI PHOTO FILM CO., LTD. (JP) 1997-03-18 US disclosed
EP-0531580-B1 Dye-donor element for use according to thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1996-08-07 EP disclosed
EP-0573080-B1 Dye-donor element for use according to thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1996-03-13 EP disclosed
EP-0308750-B1 Base precursor and light-sensitive material containing base precursor FUJI PHOTO FILM CO LTD (JP) 1995-12-13 EP disclosed
EP-0404192-B1 Light-sensitive material containing silver halide, reducing agent, polymerizable compound and base precursor FUJI PHOTO FILM CO LTD (JP) 1995-08-23 EP disclosed
EP-0383358-B1 Light-sensitive material containing silver halide reducing agent and polymerizable compound FUJI PHOTO FILM CO LTD (JP) 1995-04-26 EP disclosed
US-5397676-A Image forming method including heat development while covering surface of light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1995-03-14 US disclosed
US-4473631-A Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4463079-A Heat developable color photographic materials with redox dye releasers FUJI PHOTO FILM CO., LTD. (JP) 1984-07-31 US disclosed
US-4455363-A Heat-developable color photographic material with polymeric color coupler FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
EP-0106357-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-04-25 EP disclosed
EP-0106211-A2 Heat developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-04-25 EP disclosed
US-4430415-A Heat-developable photographic material with fine droplets containing silver halide, organic silver salt oxidizing agent and color image forming substance FUJI PHOTO FILM CO., LTD. (JP) 1984-02-07 US disclosed
EP-0079056-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1983-05-18 EP disclosed
EP-0076492-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1983-04-13 EP disclosed
EP-0067455-A1 Heat-developable color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1982-12-22 EP disclosed
EP-0066282-A1 Heat-developable color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1982-12-08 EP disclosed