Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409975 | 0.93 | IGF1R (0.46) | IGF1RCDK4CDK2 | |
| SCHEMBL408611 | 0.91 | IGF1R (0.47) | IGF1RCDK4CDK2 | |
| SCHEMBL411741 | 0.91 | TGFBR1 (0.47) | IGF1RCSF1R | |
| SCHEMBL27615247 | 0.90 | IGF1R (0.43) | IGF1RCDK4CDK2 | |
| SCHEMBL415377 | 0.90 | IGF1R (0.43) | IGF1RCDK4CDK2 | |
| SCHEMBL412686 | 0.88 | IGF1R (0.49) | IGF1RCDK4CDK2 | |
| SCHEMBL411997 | 0.87 | CYP1A2 (0.42) | IGF1R | |
| SCHEMBL413069 | 0.87 | IGF1R (0.47) | IGF1RCDK4CDK2 | |
| SCHEMBL414374 | 0.86 | IGF1R (0.46) | IGF1RCDK4CDK2 | |
| SCHEMBL411784 | 0.86 | IGF1R (0.47) | IGF1RCDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021519-A1 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-26 | — | — | US | disclosed |