Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 6/20 | 0.65 |
| ▸ | HTR7 | P34969 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374186 | 0.99 | HDAC1 (0.76) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL1376558 | 0.99 | HDAC1 (0.76) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL4126191 | 0.97 | SMN1; SMN2 (0.75) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL3995728 | 0.92 | MEN1 (0.76) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL12432012 | 0.88 | ALDH1A1 (0.68) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL12431958 | 0.88 | ALDH1A1 (0.68) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL4125967 | 0.86 | HDAC1 (0.97) | HDAC1SMN1; SMN2MEN1KMT2AHTR1A | |
| SCHEMBL4119827 | 0.85 | MAPT (0.80) | HDAC1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1375222 | 0.85 | HDAC1 (0.63) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E | |
| SCHEMBL12150979 | 0.85 | HDAC1 (0.63) | HDAC1SMN1; SMN2ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694329-A4 | DIAMINE AND IMINODIACETIC ACID HYDROXAMIC ACID DERIVATES | ATON PHARMA INC (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090023718-A1 | Diamine and Iminodiacetic Acid Hydroxamic Acid Derivatives | ATON PHARMA, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| US-20090023718-A1 | Diamine and Iminodiacetic Acid Hydroxamic Acid Derivatives | ATON PHARMA, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| US-20090023718-A1 | Diamine and Iminodiacetic Acid Hydroxamic Acid Derivatives | ATON PHARMA, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| EP-1694329-A2 | DIAMINE AND IMINODIACETIC ACID HYDROXAMIC ACID DERIVATES | Aton Pharma, Inc. (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005053610-A2 | DIAMINE AND IMINODIACETIC ACID HYDROXAMIC ACID DERIVATIVES | ATON PHARMA, INC. (US) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023718-A1 | Diamine and Iminodiacetic Acid Hydroxamic Acid Derivatives | AADAC, BRDT, HDAC5 | HDAC1 5/4885SMN1; SMN2 642/4885ALDH1A1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.