Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.40 |
| ▸ | TUBB | P07437 | 5/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128731 | 0.88 | MAPK14 (0.47) | IKBKBRXRBRXRATUBB4ATUBB | |
| SCHEMBL11775066 | 0.86 | ALDH1A1 (0.46) | IKBKBKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL5013824 | 0.85 | MAPK14 (0.46) | IKBKBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5013821 | 0.84 | MAPK14 (0.42) | IKBKBRXRBRXRATUBB4ATUBB | |
| SCHEMBL5013667 | 0.79 | MAPK14 (0.41) | IKBKBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4114697 | 0.77 | PTPN1 (0.64) | IKBKBRXRBRXRA | |
| SCHEMBL4121822 | 0.74 | SLC6A4 (0.55) | IKBKBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13606326 | 0.74 | HDAC7 (0.48) | IKBKBKDM4EALDH1A1NPSR1ACLY | |
| SCHEMBL13773460 | 0.72 | PDE4B (0.49) | IKBKBRXRBRXRAALDH1A1L3MBTL1 | |
| SCHEMBL30388543 | 0.72 | RXRB (0.64) | RXRBRXRACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | GLRA1, GLRB, GPBAR1 | IKBKB 1157/4885RXRB 239/4885RXRA 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.