Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118397 | 0.93 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2B | |
| Trifluoroacetic Acid SCHEMBL4132934 | 0.92 | ADORA2A (0.85) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL12003199 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4124320 | 0.91 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1401980 | 0.90 | ADORA2A (0.81) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL242825 | 0.88 | ADORA2A (0.81) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1402026 | 0.87 | ADORA2A (0.65) | ADORA2AADORA3ADORA1 | |
| SCHEMBL4118708 | 0.86 | ADORA2A (0.64) | ADORA2AADORA3ADORA1 | |
| SCHEMBL1401976 | 0.86 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL243109 | 0.86 | ADORA2A (0.63) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099214-A1 | Organic Compounds | NOVARTIS AG | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099214-A1 | Organic Compounds | CYP3A43, OXER1, OPRM1 | ADORA2A 2082/4885ADORA3 554/4885ADORA1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.