Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.70 |
| ▸ | POLB | P06746 | 8/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133300 | 1.00 | MEN1 (0.70) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4128122 | 0.93 | MEN1 (0.70) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4128120 | 0.93 | MEN1 (0.70) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4130334 | 0.92 | MAPK1 (0.60) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4130332 | 0.92 | MAPK1 (0.60) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4142261 | 0.91 | MEN1 (0.71) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4142257 | 0.91 | MEN1 (0.71) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4126817 | 0.89 | MEN1 (0.67) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4126818 | 0.89 | MEN1 (0.67) | MEN1KMT2APOLBMAPK1L3MBTL1 | |
| SCHEMBL4138637 | 0.87 | MAPK1 (0.72) | MEN1KMT2APOLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | KOTNIK MIHA | 2009-10-01 | — | — | US | disclosed |
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | KOTNIK MIHA | 2009-10-01 | — | — | US | disclosed |
| EP-1916249-A1 | 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents | LEK Pharmaceuticals D.D. (SI) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | XDH, TXLNA, Q6ZSR9 | MEN1 2336/4885KMT2A 1459/4885POLB 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.