⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444699 | 1.00 | — | — | |
| SCHEMBL4812082 | 0.85 | TYMS (0.50) | — | |
| SCHEMBL4822895 | 0.78 | GABBR2 (0.45) | — | |
| SCHEMBL21385310 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL16655122 | 0.76 | LPAR3 (0.33) | — | |
| SCHEMBL10376827 | 0.74 | BTN3A1 (0.41) | — | |
| SCHEMBL1731352 | 0.74 | — | — | |
| Phosphoric Acid SCHEMBL29790870 | 0.74 | LPAR3 (0.36) | — | |
| SCHEMBL1731355 | 0.74 | — | — | |
| SCHEMBL4610664 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222257-B2 | Phosphono-pent-2-en-1-yl nucleosides and analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-17 | — | — | US | disclosed |
| US-20090215726-A1 | Phosphono-Pent-2-en-1-yl Nucleosides and Analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-27 | — | — | US | disclosed |