Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 11/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133487 | 0.78 | CCR1 (0.41) | SLC6A9CCR1TRPV4FBP1 | |
| SCHEMBL4139656 | 0.74 | TRPV4 (0.40) | CCR1TRPV4GAA | |
| SCHEMBL14605682 | 0.74 | CCR1 (0.43) | SLC6A9CCR1TRPV4GAAFBP1 | |
| SCHEMBL4142748 | 0.73 | TRPV4 (0.49) | TRPV4GAA | |
| SCHEMBL4135576 | 0.72 | TP53 (0.43) | TRPV4GAA | |
| SCHEMBL4127509 | 0.71 | TRPV4 (0.41) | TRPV4GAA | |
| SCHEMBL4133641 | 0.71 | CCR1 (0.40) | CCR1TRPV4 | |
| Hydrochloric Acid SCHEMBL4136144 | 0.71 | CCR1 (0.45) | CCR1TRPV4GAA | |
| SCHEMBL4141257 | 0.68 | CCR1 (0.41) | CCR1TRPV4GAA | |
| Hydrochloric Acid SCHEMBL4136148 | 0.68 | TRPV4 (0.46) | CCR1TRPV4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | claimed |
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | SLC6A9 1356/4885CCR1 766/4885TRPV4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.