Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14122192 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBGAAPPARANPC1 | |
| SCHEMBL11212441 | 0.86 | POLB (0.63) | SMN1; SMN2POLBGAAPPARANPC1 | |
| SCHEMBL14121623 | 0.85 | POLB (0.47) | SMN1; SMN2POLBGAANPC1RAB9A | |
| SCHEMBL30300637 | 0.85 | POLB (0.47) | SMN1; SMN2POLBGAANPC1RAB9A | |
| SCHEMBL14121621 | 0.85 | POLB (0.47) | SMN1; SMN2POLBGAANPC1RAB9A | |
| SCHEMBL14122831 | 0.85 | POLB (0.47) | SMN1; SMN2POLBGAANPC1RAB9A | |
| SCHEMBL30300736 | 0.85 | POLB (0.47) | SMN1; SMN2POLBGAANPC1RAB9A | |
| SCHEMBL8935915 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAPPARAPPARGPTGDR2 | |
| SCHEMBL8935907 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAPPARAPPARGPTGDR2 | |
| SCHEMBL6863626 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBGAAPPARANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005672-A1 | ANTIDIABETIC AZAINDOLES AND DIAZAINDOLES | MERCK & CO., INC. (US) | 2009-01-08 | — | — | WO | disclosed |