Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935915 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2PPARATSHRCYP2C9TDP1 | |
| SCHEMBL8935696 | 0.87 | PPARA (0.61) | SMN1; SMN2PPARATSHRPPARGHTR2B | |
| SCHEMBL8935691 | 0.87 | PPARA (0.61) | SMN1; SMN2PPARATSHRPPARGHTR2B | |
| SCHEMBL24418979 | 0.85 | TSHR (0.49) | SMN1; SMN2PPARATSHRCYP2C9TDP1 | |
| SCHEMBL4133846 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2PPARACYP2C9TDP1PPARG | |
| SCHEMBL14122192 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2PPARACYP2C9TDP1PPARG | |
| SCHEMBL6097869 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARATSHRPPARGHTR2B | |
| SCHEMBL5861916 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARAPPARGPTGDR2LTB4R | |
| SCHEMBL2597641 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARATSHRPPARGHTR2B | |
| SCHEMBL3879629 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARATSHRTDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |