SCHEMBL4134092

SCHEMBL4134092

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nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.34
ABCB1 P08183 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28839149 1.00 TDP1 (0.53) TDP1POLBMAPK1ABCB1
SCHEMBL14661288 1.00 TDP1 (0.53) TDP1POLBMAPK1ABCB1
SCHEMBL14661031 1.00 TDP1 (0.53) TDP1POLBMAPK1ABCB1
SCHEMBL9775304 0.92 TDP1 (0.49) TDP1POLBMAPK1ABCB1
SCHEMBL13893402 0.86 TDP1 (0.71) TDP1POLBMAPK1ABCB1
SCHEMBL29529175 0.86 TDP1 (0.71) TDP1POLBMAPK1ABCB1
SCHEMBL60713 0.86 TDP1 (0.71) TDP1POLBMAPK1ABCB1
SCHEMBL15653578 0.86 TDP1 (0.71) TDP1POLBMAPK1ABCB1
SCHEMBL426635 0.86 TDP1 (0.71) TDP1POLBMAPK1ABCB1
SCHEMBL421756 0.86 TDP1 (0.71) TDP1POLBMAPK1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220025185-A1 SPECIFICALLY GLYCO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY UNIVERSITAT HAMBURG (DE) 2022-01-27 US disclosed
EP-3894421-A1 SPECIFICALLY GLYCO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY Universität Hamburg (DE) 2021-10-20 EP disclosed
WO-2020120474-A1 SPECIFICALLY GLYCO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY UNIVERSITÄT HAMBURG (DE) 2020-06-18 WO disclosed
EP-2616065-B1 GLYCO-SUBSTITUTED DIHYDROXY-CHLORINS AND B-FUNCTIONALIZED CHLORINS FOR ANTI-MICROBIAL PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2017-11-01 EP disclosed
US-9308185-B2 Glyco-substituted dihydroxy-chlorins and β-functionalized chlorins for anti-microbial photodynamic therapy BIOLITEC PHARMA MARKETING LTD (MY) 2016-04-12 US disclosed
EP-2616065-A1 GLYCO-SUBSTITUTED DIHYDROXY-CHLORINS AND B-FUNCTIONALIZED CHLORINS FOR ANTI-MICROBIAL PHOTODYNAMIC THERAPY Biolitec Pharma Marketing Ltd (MY) 2013-07-24 EP disclosed
WO-2013015774-A1 GLYCO-SUBSTITUTED DIHYDROXY-CHLORINS AND B-FUNCTIONALIZED CHLORINS FOR ANTI-MICROBIAL PHOTODYNAMIC THERAPY BIOLITEC PHARMA MARKETING LTD (MY) 2013-01-31 WO disclosed
US-20090206245-A1 Mass analysis method using fine metal particles SHIONOGI CO., LTD (JP) 2009-08-20 US disclosed
EP-1731905-A1 MASS ANALYSIS METHOD USING FINE METAL PARTICLES Shionogi Co., Ltd. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090206245-A1 Mass analysis method using fine metal particles OSTC, ZKSCAN2, SLC17A5 TDP1 4456/4885POLB 2545/4885MAPK1 3007/4885
US-20220025185-A1 SPECIFICALLY GLYCO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY B3GAT3, ST6GAL1, ST3GAL3 TDP1 1747/4885POLB 2644/4885MAPK1 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.