SCHEMBL426635

SCHEMBL426635

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nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
ABCB1 P08183 1/20 0.40
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15653578 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL15484170 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL29529175 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL60713 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL421756 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL13893402 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1
Potassium SCHEMBL30587676 0.98 TDP1 (0.69) TDP1ABCB1POLBMAPK1
Hydrochloric Acid SCHEMBL30259230 0.98 TDP1 (0.69) TDP1ABCB1POLBMAPK1
SCHEMBL8587285 0.95 TDP1 (0.68) TDP1ABCB1POLBMAPK1
SCHEMBL2279600 0.95 TDP1 (0.68) TDP1ABCB1POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812628-A Mannosylated seryl cystatin dioleamine compound, and preparation method and application thereof 制能(北京)生物科技有限公司 2024-10-22 CN claimed
CN-118724988-A Glycosylated amino acid preparation method and glycosylated polypeptide preparation method 上海科泽永欣生物科技有限公司 2024-10-01 CN claimed
CN-104031108-B A kind of fluorescent chemicals and preparation method thereof and the methods and applications utilizing this fluorescent chemicals to prepare sense film SHAANXI NORMAL UNIVERSITY (CN) 2016-04-13 CN claimed
US-20130217640-A1 GLYCOSYLATED ACETAMINOPHEN PRO-DRUG NuTek Pharma Ltd. 2013-08-22 US claimed
WO-2012012339-A2 GLYCOSYLATED ACETAMINOPHEN PRO-DRUG ANALOGS NuTek Pharma Ltd. (US) 2012-01-26 WO claimed
CN-100591812-C Preparation method of glycosylated nano-fibre for identifying protein and applications UNIV ZHEJIANG 2010-02-24 CN claimed
CN-100444942-C Glycosylated polyethylene affinity membrane preparing method and its use UNIV ZHEJIANG (CN) 2008-12-24 CN claimed
CN-101285221-A Preparation method of glycosylated nano-fibre for identifying proteinicsubstance and applications UNIV ZHEJIANG (CN) 2008-10-15 CN claimed
CN-1935342-A Glycosylated polyethylene affinity membrane preparing method and its use UNIV ZHEJIANG (CN) 2007-03-28 CN claimed
JP-5301905-A None JP disclosed
US-12617813-B2 Glycosylated histone deacetylase inhibitors and methods of making and using the same GEORGIA TECH RESEARCH CORPORATION (US) 2026-05-05 US disclosed
EP-4698568-A1 PARTICLES OF HYDROPHOBIC-CHAIN-MODIFIED MONOSACCHARIDES AND CYCLODEXTRIN Paris Sciences et Lettres (FR) 2026-02-25 EP disclosed
EP-4662322-A1 SQUARAMIDE-MODIFIED ADENO-ASSOCIATED VIRUS VECTORS Coave Therapeutics (FR) 2025-12-17 EP disclosed
US-20250236685-A1 DEGRADABLE POLYMERS THE TRUSTEES OF BOSTON COLLEGE 2025-07-24 US disclosed
JP-H05301905-A HCG-RELATING NONASACCHARINE HAPTEN TOWA KASEI KOGYO KK 1993-11-16 JP disclosed
EP-0537187-A1 PROCESS FOR PRODUCING ACYLATED GLYCOSYL FLUORIDES. HOECHST AG (DE) 1993-04-21 EP disclosed
WO-1992000308-A1 PROCESS FOR PRODUCING ACYLATED GLYCOSYL FLUORIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-09 WO disclosed
US-4873322-A VIRICIDES, HERPES AND INFLUENZA; LINKED TO CEPHALIN COMPONENTS CIBA-GEIGY CORPORATION (US) 1989-10-10 US disclosed
EP-0095904-B1 DETERGENT LIQUORS AND COMPOSITIONS FOR USE THEREIN THE PROCTER & GAMBLE COMPANY (US) 1986-09-03 EP disclosed
US-4228274-A 1-Substituted glycopyranosides MERCK & CO., INC. (US) 1980-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617813-B2 Glycosylated histone deacetylase inhibitors and methods of making and using the same HDAC3, HDAC1, HDAC11 TDP1 1940/4885ABCB1 2909/4885POLB 1351/4885
US-20130217640-A1 GLYCOSYLATED ACETAMINOPHEN PRO-DRUG UGT1A3, GCG, UGGT1 TDP1 2617/4885ABCB1 51/4885POLB 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.