SCHEMBL4134529

SCHEMBL4134529

c1cc2cc3scnc3cc2o1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 5/20 0.39
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP2A6 P11509 3/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
NFKB1 P19838 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
CYP2C19 P33261 1/20 0.36
APP P05067 1/20 0.35
CDK9 P50750 1/20 0.34
HSPD1 P10809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4138533 0.93 DYRK1A (0.39) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL4296143 0.76 ALDH1A1 (0.52) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL15834699 0.72 DYRK1A (0.42) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL18710589 0.72 ALDH1A1 (0.38) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
Benzofuran SCHEMBL28271474 0.71 ALDH1A1 (0.61) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL1156175 0.71 ALDH1A1 (0.56) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL7787699 0.71 DYRK1A (0.44) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL4560336 0.69 ALDH1A1 (0.50) DYRK1AHSD17B10ALDH1A1KDM4ENPC1
SCHEMBL2149910 0.68 CYP2A6 (0.54) DYRK1AHSD17B10KDM4ECYP2A6CYP3A4
SCHEMBL4137601 0.68 DYRK1A (0.42) DYRK1AHSD17B10ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20090092766-A1 GRAFT PATTERN FORMING METHOD AND CONDUCTIVE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2009-04-09 US disclosed
WO-2006123834-A2 GRAFT PATTERN FORMING METHOD AND CONDUCTIVE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2006-11-23 WO disclosed
EP-1061411-B1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO LTD (JP) 2006-10-11 EP disclosed
US-20050271987-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
US-6838231-B2 Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-04 US disclosed
US-20040166450-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. 2004-08-26 US disclosed
US-6780577-B2 A MULTILAYER COMPRISING PHOTOSENSITIVE DYES WITH ABSORPTION SPECTRA AT A HIGH FLUORESCENCE WAVELENGTH FUJI PHOTO FILM CO., LTD. (JP) 2004-08-24 US disclosed
US-6730468-B1 ADSORBED ON SURFACE A SENSITIZING DYE IN MULTIPLE LAYERS FUJI PHOTO FILM CO., LTD. (JP) 2004-05-04 US disclosed
US-20030180673-A1 Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2003-09-25 US disclosed
US-20030170575-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. 2003-09-11 US disclosed
US-6610466-B2 Exhibits increased light absorption and light absorption intensity and which has sensitizing dyes adsorbed in multilayer form stably even in the presence of an organic solvent. FUJI PHOTO FILM CO., LTD. (JP) 2003-08-26 US disclosed
US-6582894-B1 Silver haide photographic emulsion and photographic light-sensitive material using same FUJI PHOTO FILM CO., LTD. (JP) 2003-06-24 US disclosed
US-6521401-B1 Spectrally sensitizing with dye that does not have electric charge or forms an inner salt FUJI PHOTO FILM CO., LTD. (JP) 2003-02-18 US disclosed
US-20020177087-A1 Silver halide photographic lightsensitive material FUJIFILM CORPORATION (JP) 2002-11-28 US disclosed
US-6465166-B1 HIGH SPEED SILVER HALIDE PHOTOGRAPHIC EMULSION WHEREIN THE GRAIN AGGLOMERATION IS PREVENTED AND PHOTOGRAPHIC MATERIAL REDUCED IN RESIDUAL DYE COLOR AFTER PROCESSING FUJI PHOTO FILM. CO., LTD. (JP) 2002-10-15 US disclosed
US-20020012892-A1 Methine compound-containing silver halide photographic emulsion and photographic material using the same FUJIFILM CORPORATION (JP) 2002-01-31 US disclosed
EP-1067430-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. (JP) 2001-01-10 EP disclosed
EP-1061411-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. (JP) 2000-12-20 EP disclosed