Clorethate

Clorethate

SCHEMBL41346

O=C(OCC(Cl)(Cl)Cl)OCC(Cl)(Cl)Cl

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
ALDH1A1 P00352 3/20 0.38
POLB P06746 1/20 0.34
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22228982 0.89 CHRM2 (0.35) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL4389209 0.87 CHRM2 (0.34) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL8083410 0.87 HTT (0.48) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL575139 0.87 ALDH1A1 (0.62) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL11237526 0.85 CHRM2 (0.36) CHRM2CHRM4CHRM1CHRM3
SCHEMBL4290461 0.85 CHRM2 (0.33) CHRM2CHRM4CHRM1CHRM3
SCHEMBL7148590 0.85 TSHR (0.37) CHRM2CHRM4CHRM1CHRM3TSHR
SCHEMBL7148588 0.85 CHRM2 (0.33) CHRM2CHRM4CHRM1CHRM3
SCHEMBL11839244 0.85 TSHR (0.33) CHRM2CHRM4CHRM1CHRM3TSHR
SCHEMBL575201 0.84 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4956 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
WO-2024150170-A1 PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2024-07-18 WO claimed
US-20240238250-A1 METHOD OF USING PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2024-07-18 US claimed
US-11834470-B2 4-thioribose NAD analogues and methods of synthesizing and using the same UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-12-05 US claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 US claimed
CN-111983975-B Spline curve interpolation method for parameter increment compensation 江苏威泽智能科技股份有限公司 2023-04-18 CN claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 US claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-5710247-A DEPROTECTING OLIGOPEPTIDE; COUPLING ABBOTT LABORATORIES (US) 1998-01-20 US claimed
US-5710246-A COUPLING OLIGOPEPTIDES; DEPROTECTING ABBOTT LABORATORIES (US) 1998-01-20 US claimed
WO-1997041879-A1 ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
WO-1997034924-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1997-09-25 WO claimed
WO-1997034923-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1997-09-25 WO claimed
US-5446134-A Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1995-08-29 US claimed
US-5401858-A Preparation of quinic acid derivatives NESTEC S.A. (CH) 1995-03-28 US claimed
US-5395950-A Production of quinic acid derivatives NESTEC S.A. (CH) 1995-03-07 US claimed
EP-0581979-A1 Quinic acid derivatives and process to prepare quinic acid derivatives SOCIETE DES PRODUITS NESTLE S.A. (CH) 1994-02-09 EP claimed
EP-0581980-A1 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid SOCIETE DES PRODUITS NESTLE S.A. (CH) 1994-02-09 EP claimed