SCHEMBL4135128

SCHEMBL4135128

CCOC(=O)C(C#N)=COC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.61
ALDH1A1 P00352 9/20 0.50
TSHR P16473 1/20 0.50
PKM P14618 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 5/20 0.48
MAPT P10636 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
POLB P06746 1/20 0.48
PTP4A1 Q93096 1/20 0.48
MIF P14174 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
GAA P10253 2/20 0.47
USP2 O75604 1/20 0.47
PDCD1 Q15116 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546680 1.00 CYP2C9 (0.61) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL31636860 1.00 CYP2C9 (0.61) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL28234514 0.89 CYP2C9 (0.50) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL11656823 0.85 CYP2C9 (0.45) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL666831 0.85 CYP2C9 (0.45) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL167037 0.85 CYP2C9 (0.61) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL167036 0.85 CYP2C9 (0.61) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL508463 0.85 CYP2C9 (0.61) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL4906704 0.84 CYP2C9 (0.69) CYP2C9ALDH1A1TSHRPKMHTT
SCHEMBL4961560 0.84 CYP2C9 (0.69) CYP2C9ALDH1A1TSHRPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390105-A1 METHODS AND DEVICES FOR CONTROLLED DELIVERY POINTILLIST GLOBAL MACRO SERIES OF POINTILLIST PARTNERS LLC 2023-12-07 US claimed
CN-114561154-B UV (ultraviolet) and moisture dual-solid instant adhesive and preparation method thereof 浙江久而久化学有限公司 2022-10-28 CN claimed
CN-114561154-A UV (ultraviolet) and moisture dual-solid instant adhesive and preparation method thereof 浙江久而久化学有限公司 2022-05-31 CN claimed
EP-3898736-A1 COMPOSITION COMPRISING CYANOACRYLATES AND AT LEAST ONE BLOCK COPOLYMER ARKEMA FRANCE (FR) 2021-10-27 EP claimed
WO-2020128349-A1 COMPOSITION COMPRISING CYANOACRYLATES AND AT LEAST ONE BLOCK COPOLYMER ARKEMA FRANCE (FR) 2020-06-25 WO claimed
US-10471174-B2 Cyanoacrylate medical adhesive and preparation method and use thereof Shen, Wei (CN) 2019-11-12 US claimed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP claimed
CN-106966976-B A kind of preparation method of Methylbenzoquate 浙江金伯士药业有限公司 2019-10-18 CN claimed
US-20190175782-A1 NOVEL CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN, WEI (CN) 2019-06-13 US claimed
EP-3335738-A1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Shen, Wei (CN) 2018-06-20 EP claimed
US-8652225-B2 Flexible coated abrasive finishing article and method of manufacturing the same MACKAY JOSEPH H (US) 2014-02-18 US claimed
CN-101765407-A Mesh dispenser CLOSURE MEDICAL CORP 2010-06-30 CN claimed
US-7238363-B2 Modification of medical prostheses BAYLOR COLLEGE OF MEDICINE (US) 2007-07-03 US claimed
EP-1737378-A2 NOVEL MODIFICATION OF MEDICAL PROSTHESES Baylor College of Medicine (US) 2007-01-03 EP claimed
US-20050271694-A1 Novel modification of medical prostheses BAYLOR COLLEGE OF MEDICINE 2005-12-08 US claimed
WO-2005096990-A2 NOVEL MODIFICATION OF MEDICAL PROSTHESES BAYLOR COLLEGE OF MEDICINE (US) 2005-10-20 WO claimed
WO-2003006236-A1 COMPONENT OF PRINTED CIRCUIT BOARDS GOULD ELECTRONICS INC. (US) 2003-01-23 WO claimed
US-20030017357-A1 Component of printed circuit boards GOULD ELECTRONICS INC. 2003-01-23 US claimed
US-5879774-A DIGITAL VERSATILE DISK (DVD) OPTICAL RECORDING ELEMENT MADE WITH A CURED CYANOACRYLATE ADHESIVE AND CONTAINING AN UNSATURATED POLYMERIC PROTECTIVE LAYER HAVING A MONOMER CONTAINING AMINE GROUPS AS A CURE ACCELERATOR; NONWARPING EASTMAN KODAK COMPANY (US) 1999-03-09 US claimed
US-4933220-A Using cyanoacrylate ARMSTRONG WORLD INDUSTRIES, INC. (US) 1990-06-12 US claimed