SCHEMBL666831

SCHEMBL666831

CCCOC(=O)C(C#N)=COC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.45
DNM1 Q05193 3/20 0.38
ALDH1A1 P00352 6/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NPSR1 Q6W5P4 3/20 0.37
TP53 P04637 1/20 0.36
MAPT P10636 5/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PTP4A1 Q93096 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MIF P14174 1/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
USP2 O75604 2/20 0.36
GAA P10253 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11656823 1.00 CYP2C9 (0.45) CYP2C9DNM1ALDH1A1PKMHTT
SCHEMBL7547812 0.90 TP53 (0.45) CYP2C9DNM1ALDH1A1PKMHTT
SCHEMBL540752 0.90 TP53 (0.45) CYP2C9DNM1ALDH1A1PKMHTT
SCHEMBL20261950 0.87 TSHR (0.47) CYP2C9DNM1NPSR1TP53MAPT
SCHEMBL4546680 0.85 CYP2C9 (0.61) CYP2C9ALDH1A1PKMHTTNPC1
SCHEMBL4135128 0.85 CYP2C9 (0.61) CYP2C9ALDH1A1PKMHTTNPC1
SCHEMBL31636860 0.85 CYP2C9 (0.61) CYP2C9ALDH1A1PKMHTTNPC1
SCHEMBL23941236 0.85 CYP2C9 (0.50) CYP2C9DNM1ALDH1A1PKMHTT
SCHEMBL28852642 0.85 CYP2C9 (0.50) CYP2C9DNM1ALDH1A1PKMHTT
SCHEMBL11652946 0.84 CYP2C9 (0.47) CYP2C9DNM1ALDH1A1PKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056626-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2010-03-04 US claimed
EP-2081567-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES Metis S.r.l. (IT) 2009-07-29 EP claimed
WO-2008059541-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2008-05-22 WO claimed
CN-113874459-B Flexible photocurable cyanoacrylate compositions 汉高股份有限及两合公司 2023-07-04 CN disclosed
US-9402762-B2 Methods and devices for conduit occlusion FEMASYS INC. 2016-08-02 US disclosed
US-9220880-B2 Methods and devices for delivery of compositions to conduits FEMASYS INC. (US) 2015-12-29 US disclosed
US-20150068531-A1 METHODS AND DEVICES FOR CONDUIT OCCLUSION FEMASYS INC. (US) 2015-03-12 US disclosed
US-8726906-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2014-05-20 US disclosed
US-20130225977-A1 Methods and Devices for Delivery of Compositions to Conduits FEMASYS INC. (US) 2013-08-29 US disclosed
US-20130220335-A1 Methods and Devices for Conduit Occlusion FEMASYS INC. (US) 2013-08-29 US disclosed
US-8336552-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2012-12-25 US disclosed
EP-1838353-A2 TOPICAL ADMINISTRATION PERMITTING PROLONGED EXPOSURE OF TARGET CELLS TO THERAPEUTIC AND PROPHYLACTIC NUCLEIC ACIDS Introgen Therapeutics, Inc. (US) 2007-10-03 EP disclosed
US-20070066552-A1 Topical administration permitting prolonged exposure of target cells to therapeutic and prophylactic nucleic acids INTROGEN THERAPEUTICS, INC. 2007-03-22 US disclosed
WO-2006079014-A2 TOPICAL ADMINISTRATION PERMITTING PROLONGED EXPOSURE OF TARGET CELLS TO THERAPEUTIC AND PROPHYLACTIC NUCLEIC ACIDS INTROGEN THERAPEUTICS, INC. (US) 2006-07-27 WO disclosed
US-6723114-B2 CONTAINING ETHYLENE GLYCOL OXALATE COPOLYMER; BIOABSORBABLE OR BIODEGRADABLE; REDUCED REACTIONS AND FOREIGN BODY RESPONSES POLY-MED, INC. 2004-04-20 US disclosed
US-6699940-B2 Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom POLY MED, INC. 2004-03-02 US disclosed
US-20030105256-A1 Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom POLY-MED, INC. 2003-06-05 US disclosed
US-20020116026-A1 Polyester/cyanoacrylate tissue adhesive formulations POLY-MED, INC. 2002-08-22 US disclosed
US-6299631-B1 USEFUL AS TISSUE ADHESIVE/SEALANTS, HEMOSTATIC AGENTS, AND AS A MEANS FOR PATCHING OR ANASTOMIC COUPLING OF DAMAGED ORGANS; BIOABSORPTION POLY-MED, INC. 2001-10-09 US disclosed
US-4104049-A Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed