Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4135167

CCOc1cc(C(Oc2ccc(N(C=N)C(=O)O)cc2)C(=O)NCc2ccccc2)ccc1OC(C)C.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F7 P08709 13/20 0.44
F3 P13726 11/20 0.44
F2 P00734 10/20 0.44
F10 P00742 10/20 0.44
F11 P03951 8/20 0.44
PRSS1 P07477 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
OPRK1 P41145 3/20 0.38
OPRM1 P35372 2/20 0.38
OPRD1 P41143 2/20 0.38
KLKB1 P03952 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2538019 0.85 F2 (0.59) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL2538391 0.84 F7 (0.46) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL4655945 0.83 F7 (0.47) F7F3F2F10F11
SCHEMBL2536769 0.79 F7 (0.64) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL4657077 0.79 F7 (0.53) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL2539624 0.77 F7 (0.54) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL2541458 0.76 F7 (0.52) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL2539699 0.76 F7 (0.50) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL2543814 0.72 F7 (0.45) F7F3F2F10F11
Trifluoroacetic Acid SCHEMBL15643025 0.71 F7 (0.54) F7F3F2F10F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996541-B1 2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL MYERS SQUIBB CO (US) 2014-04-23 EP disclosed
US-20090131473-A1 2-(ARYLOXY) ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY 2009-05-21 US disclosed
EP-1996541-A1 2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS Bristol-Myers Squibb Company (US) 2008-12-03 EP disclosed
WO-2007103996-A1 2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131473-A1 2-(ARYLOXY) ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS F7, F9, F12 F7 1/4885F3 11/4885F2 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.