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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4655945

CCOc1cc(C(Oc2ccc(C(=N)NC(=O)O)cc2)C(=O)NCc2ccccc2)ccc1OC(C)C.O=C(O)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 12/20 0.47
▸ F2 P00734 9/20 0.47
▸ F10 P00742 9/20 0.47
▸ PRSS1 P07477 4/20 0.47
▸ F3 P13726 8/20 0.45
▸ F11 P03951 5/20 0.45
▸ OPRK1 P41145 3/20 0.40
▸ OPRM1 P35372 2/20 0.40
▸ OPRD1 P41143 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ KLKB1 P03952 1/20 0.38
▸ PRSS2 P07478 1/20 0.38
▸ PRSS3 P35030 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2538019 0.91 F2 (0.59) F7F2F10PRSS1F3
Trifluoroacetic Acid SCHEMBL2538391 0.87 F7 (0.46) F7F2F10PRSS1F3
SCHEMBL2536769 0.85 F7 (0.64) F7F2F10PRSS1F3
Trifluoroacetic Acid SCHEMBL4135167 0.83 F7 (0.44) F7F2F10PRSS1F3
Trifluoroacetic Acid SCHEMBL2541458 0.82 F7 (0.52) F7F2F10PRSS1F3
Trifluoroacetic Acid SCHEMBL4657077 0.81 F7 (0.53) F7F2F10PRSS1F3
Trifluoroacetic Acid SCHEMBL2539624 0.78 F7 (0.54) F7F2F10PRSS1F3
SCHEMBL2544588 0.78 F7 (0.47) F7F2F10PRSS1F3
SCHEMBL2542910 0.78 F7 (0.44) F7F2F10PRSS1F3
Trifluoroacetic Acid SCHEMBL2543814 0.77 F7 (0.45) F7F2F10PRSS1F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996541-B1 2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL MYERS SQUIBB CO (US) 2014-04-23 — — EP disclosed
EP-1996541-A1 2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS Bristol-Myers Squibb Company (US) 2008-12-03 — — EP disclosed
WO-2007103996-A1 2-(ARYLOXY)ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-09-13 — — WO disclosed