Tioconazole

Tioconazole

SCHEMBL41354

Clc1ccc(C(Cn2ccnc2)OCc2ccsc2Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Tioconazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 1.00
ADORA3 P0DMS8 5/20 1.00
SLC6A2 P23975 5/20 1.00
SLC6A4 P31645 5/20 1.00
SLC6A3 Q01959 5/20 1.00
KCNH2 Q12809 5/20 1.00
NR1I2 O75469 4/20 1.00
NR3C1 P04150 4/20 1.00
CYP17A1 P05093 4/20 1.00
ADRB1 P08588 4/20 1.00
DRD2 P14416 4/20 1.00
OPRK1 P41145 4/20 1.00
DRD3 P35462 4/20 1.00
CHRM3 P20309 3/20 1.00
HTR2A P28223 3/20 1.00
OPRD1 P41143 3/20 1.00
PDE4D Q08499 3/20 1.00
TBXA2R P21731 3/20 1.00
ADRA2C P18825 2/20 1.00
ADRA1A P35348 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tioconazole SCHEMBL29882046 1.00 PGR (1.00) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL41355 1.00 PGR (1.00) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL3682100 1.00 PGR (1.00) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL29881791 1.00 PGR (1.00) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL3682098 1.00 PGR (1.00) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL29408808 1.00 PGR (1.00) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL3722115 0.99 PGR (0.98) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL7165886 0.99 PGR (0.98) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL7165888 0.99 PGR (0.98) PGRADORA3SLC6A2SLC6A4SLC6A3
Tioconazole SCHEMBL9441817 0.95 PGR (0.91) PGRADORA3SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16571 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106952-A1 METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION CDG CARE (US) 2026-05-21 WO claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-20260102419-A1 USE OF COMPOUNDS IN THE TREATMENT OF FUNGAL INFECTIONS BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2026-04-16 US claimed
EP-4719384-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES Trustees of Dartmouth College (US) 2026-04-08 EP claimed
US-20260076924-A1 COMPOSITIONS AND METHODS OF TREATMENT FOR TINEA PEDIS THERAPEUTICS INC (US) 2026-03-19 US claimed
US-20260027255-A1 Cross-Linked Telechelic Polymer Compositions, Methods of Preparation Thereof, and Methods of Using Same BETTY YU SKIN TECH ADVISORS LLC (US) 2026-01-29 US claimed
EP-4680240-A1 METHOD OF TREATING DISORDERS WITH SURF1 MALFUNCTION Cure Mito Foundation (US) 2026-01-21 EP claimed
EP-4676500-A2 MICROBIAL CONSORTIA Kanvas Biosciences, Inc (US) 2026-01-14 EP claimed
US-20260007753-A1 DERMAL SKIN PROTECTANT AND CARRIER INSPIRED MAT STRATEGIES LLC (US) 2026-01-08 US claimed
WO-1987002580-A1 FILM-FORMING, PHARMACEUTICAL VEHICLES FOR APPLICATION OF MEDICAMENTS TO NAILS, PHARMACEUTICAL COMPOSITIONS BASED ON THOSE VEHICLES, AND METHODS OF USING SAME DERMATOLOGICAL PRODUCTS OF TEXAS (US) 1987-05-07 WO claimed
US-4661493-A ECONAZOLE, CLOTRIMAZOLE, KETOCONAZOLE, BUTACONAZOLE PFIZER INC. (US) 1987-04-28 US claimed
WO-1987002219-A1 ALPHA TOCOPHEROL-BASED VESICLES THE LIPOSOME COMPANY, INC. (US) 1987-04-23 WO claimed
WO-1986005977-A1 STEROIDAL LIPOSOMES THE LIPOSOME COMPANY, INC. (US) 1986-10-23 WO claimed
EP-0196855-A2 Tioconazole and related compounds for prevention of sexually transmitted diseases and control of herpetic infections PFIZER INC. (US) 1986-10-08 EP claimed
EP-0064830-B1 PHARMACEUTICAL COMPOSITIONS FOR TREATING NAIL INFECTIONS Pfizer Limited (GB) 1986-02-26 EP claimed
EP-0165783-A1 Aromatase inhibiting N-substitued imidazole derivatives ELI LILLY AND COMPANY (US) 1985-12-27 EP claimed
EP-0064830-A2 Pharmaceutical compositions for treating nail infections Pfizer Limited (GB) 1982-11-17 EP claimed
US-4277475-A FOR BOTH MALES AND FEMALES SYNTEX (U.S.A.) INC. (US) 1981-07-07 US claimed
US-4247552-A Contraceptive compositions and methods employing 1-substituted imidazole derivatives SYNTEX (U.S.A.) INC. (US) 1981-01-27 US claimed