SCHEMBL4135573

SCHEMBL4135573

O=C(O)c1ccc(OC(=O)c2ccc(C(=O)O)cc2)cc1.O=C(O)c1cccc(C(=O)Oc2ccc(-c3ccc(O)cc3)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 4/20 0.53
TDP1 Q9NUW8 2/20 0.53
HSD17B10 Q99714 1/20 0.50
PARP10 Q53GL7 1/20 0.49
EGFR P00533 1/20 0.46
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
RAB9A P51151 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA6 P23280 2/20 0.46
CA9 Q16790 2/20 0.46
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46
DRD1 P21728 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL3853193 1.00 LMNA (0.54) LMNAGAAMAPTTDP1HSD17B10
SCHEMBL10456284 0.96 LMNA (0.57) LMNAGAAMAPTTDP1HSD17B10
Paraben SCHEMBL6850922 0.91 KMT2A (0.53) MAPTTDP1PARP10KMT2AMEN1
SCHEMBL9435811 0.91 CA12 (0.53) LMNAGAAMAPTTDP1PARP10
Paraben SCHEMBL6318342 0.90 KMT2A (0.52) LMNAGAAMAPTTDP1PARP10
SCHEMBL2345023 0.90 HSD17B10 (0.51) LMNAGAAMAPTTDP1HSD17B10
SCHEMBL6394400 0.90 HSD17B10 (0.51) LMNAGAAMAPTTDP1HSD17B10
SCHEMBL21465315 0.90 PARP10 (0.50) LMNAGAAMAPTTDP1PARP10
Paraben SCHEMBL5083113 0.89 HSD17B10 (0.61) LMNAMAPTHSD17B10PARP10EGFR
SCHEMBL14567082 0.89 HSD17B10 (0.61) LMNAMAPTHSD17B10PARP10EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983020-B1 METHOD FOR MODIFICATION OF LIQUID CRYSTAL POLYMER LEF TECHNOLOGY INC (JP) 2014-05-07 EP disclosed
US-7608371-B2 Irradiating polyesters with laser beam having pulse width of 10-12 seconds or less to improve physical strength; abrasion resistance LEF TECHNOLOGY, INC. (JP) 2009-10-27 US disclosed
US-20090048362-A1 Method of Modifying Liquid Crystal Polymers LEF TECHNOLOGY, INC. (JP) 2009-02-19 US disclosed
EP-1983020-A1 METHOD FOR MODIFICATION OF LIQUID CRYSTAL POLYMER LEF Technology Inc. (JP) 2008-10-22 EP disclosed