SCHEMBL4136909

SCHEMBL4136909

COC(O[SiH3])=C(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2478505 0.71
SCHEMBL9185775 0.66 CHRM2 (0.38)
SCHEMBL8932089 0.63
SCHEMBL8049997 0.61
SCHEMBL8049996 0.61
SCHEMBL222498 0.60
SCHEMBL6629586 0.59
SCHEMBL15105779 0.59
SCHEMBL5345064 0.58 DGAT1 (0.36)
SCHEMBL7521173 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198370-B2 Coated substrate E I DU PONT DE NEMOURS AND COMPANY (US) 2012-06-12 US disclosed
US-20090198016-A1 Coated Substrate E. I. DU PONT DE NEMOURS AND COMPANY 2009-08-06 US disclosed
US-6376230-B1 Stereoselective process for producing intermediates of cryptophycins ELI LILLY AND COMPANY 2002-04-23 US disclosed
WO-1998038158-A1 PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS ELI LILLY AND COMPANY (US) 1998-09-03 WO disclosed
EP-0861838-A2 Process and intermediates for preparing cryptophycin compounds ELI LILLY AND COMPANY (US) 1998-09-02 EP disclosed
EP-0556650-B1 Amine-containing block polymers for pigmented ink jet inks DU PONT (US) 1995-06-07 EP disclosed
US-5272201-A Amine-containing block polymers for pigmented ink jet inks E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-21 US disclosed
EP-0556650-A1 Amine-containing block polymers for pigmented ink jet inks E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-25 EP disclosed
EP-0524246-A1 RESIST MATERIAL AND PROCESS FOR USE. DU PONT (US) 1993-01-27 EP disclosed
US-5064898-A Room temperature-curable organopolysiloxane composition and method for the preparation thereof SHIN-ETSU CHEMICAL CO. (JP) 1991-11-12 US disclosed
WO-1991015810-A1 RESIST MATERIAL AND PROCESS FOR USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 WO disclosed
US-4985332-A Resist material with carbazole diazonium salt acid generator and process for use E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-15 US disclosed