Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136946 | 1.00 | GAA (0.82) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4145862 | 0.90 | GAA (0.80) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4145860 | 0.90 | GAA (0.80) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4451229 | 0.90 | GAA (0.80) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4451234 | 0.90 | GAA (0.80) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4149863 | 0.87 | KMT2A (0.68) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4149866 | 0.87 | KMT2A (0.68) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4153279 | 0.86 | MEN1 (0.85) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4153284 | 0.86 | MEN1 (0.85) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4140071 | 0.85 | GAA (0.91) | GAAALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156644-A1 | Use of thiazole derivatives and analogues in the treatment of cancer | BETAGENON AB (SE) | 2009-06-18 | — | — | US | disclosed |
| US-20090136472-A1 | Use of thiazole derivatives and analogues in disorders caused by free fatty acids | BETAGENON AB (SE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156644-A1 | Use of thiazole derivatives and analogues in the treatment of cancer | TBXA2R, TSHR, FOLR1 | GAA 2671/4885ALDH1A1 312/4885KMT2A 1742/4885 |
| US-20090136472-A1 | Use of thiazole derivatives and analogues in disorders caused by free fatty acids | FFAR2, FFAR1, FFAR4 | GAA 1211/4885ALDH1A1 707/4885KMT2A 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.