Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.50 |
| ▸ | TACR1 | P25103 | 5/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131317 | 0.82 | STS (0.56) | STSTACR1TGFBR1MAPTGPR119 | |
| SCHEMBL4137213 | 0.76 | STS (0.39) | STSTACR1TGFBR1MAPTCYP2D6 | |
| SCHEMBL3040315 | 0.72 | TACR1 (0.55) | STSTACR1MAPTCYP2D6TSHR | |
| SCHEMBL20151867 | 0.72 | TSHR (0.58) | STSTACR1MAPTCYP2D6TSHR | |
| SCHEMBL23217017 | 0.71 | STS (0.54) | STSTACR1MAPTMEN1KMT2A | |
| SCHEMBL8662177 | 0.71 | USP2 (0.58) | MAPTMEN1KMT2AALDH1A1GPR119 | |
| SCHEMBL447202 | 0.70 | CYP2D6 (0.53) | STSTACR1MAPTCYP2D6TSHR | |
| SCHEMBL3033184 | 0.70 | TACR1 (0.52) | STSTACR1MEN1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL29190718 | 0.69 | USP2 (0.56) | MAPTMEN1KMT2AALDH1A1GPR119 | |
| SCHEMBL20137044 | 0.69 | CYP2D6 (0.54) | STSTACR1MAPTCYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042899-A1 | Piperazinyl-or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase | LEHR PHILIPP | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042899-A1 | Piperazinyl-or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase | STS, SULT2A1, ARSA | STS 1/4885TACR1 1098/4885TGFBR1 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.