SCHEMBL413744

SCHEMBL413744

O=C=Nc1cccc(C(=O)Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.43
MAPT P10636 4/20 0.39
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
THRB P10828 1/20 0.39
PLCG1 P19174 1/20 0.39
CYP3A4 P08684 3/20 0.38
TRPA1 O75762 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.33
CCNE2 O96020 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1046632 0.85 TDP1 (0.48) TDP1MAPK1ALDH1A1MAPTRAB9A
SCHEMBL10478230 0.84 ALDH1A1 (0.48) TDP1MAPK1ALDH1A1TSHRMAPT
SCHEMBL4393821 0.83 MAPT (0.54) TDP1ALDH1A1MAPTRAB9ANPC1
Methane SCHEMBL7696978 0.81 MAPT (0.53) TDP1ALDH1A1MAPTRAB9ANPC1
SCHEMBL60465 0.81 KMT2A (0.47) TDP1MAPK1ALDH1A1MAPTRAB9A
Hydrochloric Acid SCHEMBL10393362 0.81 MAPT (0.53) TDP1ALDH1A1MAPTRAB9ANPC1
SCHEMBL9878695 0.81 PARP1 (0.50) TDP1MAPK1ALDH1A1TSHRMAPT
Ammonia Solution, Strong SCHEMBL27092164 0.81 MAPT (0.53) TDP1ALDH1A1MAPTRAB9ANPC1
SCHEMBL9179013 0.80 MAPK1 (0.41) TDP1MAPK1TSHRCYP3A4TRPA1
SCHEMBL890379 0.80 MAPK1 (0.41) TDP1MAPK1TSHRCYP3A4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119752386-A Polyurethane sealant for fault indicator and preparation method thereof 广州德汇新材料科技有限公司 2025-04-04 CN claimed
CN-119433749-A Preparation method and application of imidazole salt graphene modified nylon fiber 宿迁市康莱建设工程有限公司 2025-02-14 CN claimed
CN-119081283-A Flame-retardant polypropylene connecting wire sheath layer material and manufacturing method thereof 广州凡鑫电器有限公司 2024-12-06 CN claimed
CN-119391082-B High-strength stamping-resistant PP composite material and preparation method thereof 普宁市齐毫文具有限公司 2025-06-17 CN disclosed
CN-119752386-A Polyurethane sealant for fault indicator and preparation method thereof 广州德汇新材料科技有限公司 2025-04-04 CN disclosed
CN-119433749-A Preparation method and application of imidazole salt graphene modified nylon fiber 宿迁市康莱建设工程有限公司 2025-02-14 CN disclosed
CN-119391082-A High-strength stamping-resistant PP composite material and preparation method thereof 普宁市齐毫文具有限公司 2025-02-07 CN disclosed
CN-119144029-A Biodegradable environment-friendly food preservative film and manufacturing method thereof 苏州汉德瑞生物工程有限公司 2024-12-17 CN disclosed
CN-119081283-A Flame-retardant polypropylene connecting wire sheath layer material and manufacturing method thereof 广州凡鑫电器有限公司 2024-12-06 CN disclosed
US-11289238-B2 Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) 2022-03-29 US disclosed
CN-107849816-B Method for treating paperboard and paper media and related treated paperboard and paper media 巴斯夫欧洲公司 2021-07-09 CN disclosed
WO-1998008839-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed
EP-0825164-A2 Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides ELI LILLY AND COMPANY (US) 1998-02-25 EP disclosed
EP-0302341-B1 ISOCYANATO-ACYL URETHANES, THEIR PREPARATION AND USE BAYER AG (DE) 1992-05-06 EP disclosed
US-4946990-A CHEMICAL INTERMEDIATE FOR THE PRODUCTION OF POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1990-08-07 US disclosed
US-4921996-A Isocyanato-acylurethanes, a process for their preparation and their use BAYER AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
US-4886902-A HEATING POLYISOCYANATE AND AMINE WITH SILYLATED HYDROXYL GROUP; REACTING ISOCYANATE-ACID HALIDE WITH PRODUCT BAYER AKTIENGESELLSCHAFT (DE) 1989-12-12 US disclosed
US-4870198-A SILYLATED ALCOHOL OR CARBOXYL GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed
EP-0307756-A2 Process for the preparation of isocyanates and their use in the preparation of polyisocyanates containing ester groups, and some polyisocyanates containing these ester groups BAYER AG (DE) 1989-03-22 EP disclosed
EP-0302341-A2 Isocyanato-acyl urethanes, their preparation and use BAYER AG (DE) 1989-02-08 EP disclosed