SCHEMBL4137445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4137449	1.00	CYP3A4 (0.40)	CYP3A4MAPTCYP2C9CYP2C19KDM4E
	SCHEMBL4144114	0.92	NPSR1 (0.44)	CYP3A4MAPTKDM4EALDH1A1SLC6A12
	SCHEMBL4144118	0.92	NPSR1 (0.44)	CYP3A4MAPTKDM4EALDH1A1SLC6A12
	SCHEMBL4152746	0.91	DRD3 (0.47)	SLC6A12DRD3CNR1CNR2
	SCHEMBL4143662	0.91	SLC6A12 (0.40)	KDM4EALDH1A1SLC6A12DRD3KDR
	SCHEMBL4145155	0.91	USP2 (0.41)	KDM4EALDH1A1SLC6A12DRD3KDR
	SCHEMBL4152742	0.91	DRD3 (0.47)	SLC6A12DRD3CNR1CNR2
	SCHEMBL4145163	0.91	USP2 (0.41)	KDM4EALDH1A1SLC6A12DRD3KDR
	SCHEMBL4143656	0.91	SLC6A12 (0.40)	KDM4EALDH1A1SLC6A12DRD3KDR
	SCHEMBL4140651	0.91	KDM4E (0.46)	KDM4EALDH1A1SLC6A12DRD3KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.