Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151371 | 0.87 | NR3C1 (1.00) | NR3C1HTT | |
| SCHEMBL4138311 | 0.82 | NR3C1 (0.72) | NR3C1MEN1KMT2A | |
| SCHEMBL4147688 | 0.81 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1HTTMEN1 | |
| SCHEMBL4151366 | 0.81 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL4138314 | 0.80 | NR3C1 (0.66) | NR3C1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL4143729 | 0.79 | NR3C1 (1.00) | NR3C1ALDH1A1HTT | |
| SCHEMBL4151367 | 0.79 | NR3C1 (1.00) | NR3C1ALDH1A1 | |
| SCHEMBL4142930 | 0.78 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL4151237 | 0.76 | NR3C1 (0.89) | NR3C1ALDH1A1MAPK1HTTMEN1 | |
| SCHEMBL2672956 | 0.76 | NR3C1 (0.59) | NR3C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173664-B2 | Modified pyrimidine glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173664-B2 | Modified pyrimidine glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-7576076-B2 | Modified pyrimidine glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576076-B2 | Modified pyrimidine glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2009-08-18 | — | — | US | disclosed |