Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13966592 | 0.81 | CHRNA7 (0.44) | CHRNA7NPC1HRH4CYP2A6CASP3 | |
| SCHEMBL5410560 | 0.80 | NPC1 (0.54) | NPC1HRH4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5416112 | 0.78 | CYP1A2 (0.39) | NPC1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL13942162 | 0.76 | CYP2A6 (0.34) | CYP2A6CYP2C19 | |
| SCHEMBL13942151 | 0.76 | IDO1 (0.36) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL5410704 | 0.75 | CHRM3 (0.37) | — | |
| SCHEMBL3674569 | 0.75 | KMO (0.46) | NPC1DPP4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29836152 | 0.75 | KMO (0.46) | NPC1DPP4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5412658 | 0.75 | KMO (0.46) | NPC1DPP4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13942153 | 0.72 | GRM5 (0.43) | NPC1CYP1A2CYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | ALK, DPYD, DDT | CHRNA7 2645/4885NPC1 4696/4885HRH4 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.