Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | OGG1 | O15527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903691 | 0.88 | SMN1; SMN2 (0.37) | LMNAGHSRPRKCIKDM4EALDH1A1 | |
| SCHEMBL13903783 | 0.87 | PRKCI (0.38) | CRHR1MAPTLMNAPRKCIKDM4E | |
| SCHEMBL13903676 | 0.80 | PRKCI (0.35) | MAPTLMNAGHSRPRKCIKDM4E | |
| SCHEMBL4128387 | 0.79 | MAPK1 (0.33) | MAPTLMNAPRKCIKDM4EALDH1A1 | |
| SCHEMBL13903778 | 0.77 | GLP1R (0.33) | MAPTLMNAPRKCIKDM4EALDH1A1 | |
| SCHEMBL15828126 | 0.76 | MAPT (0.44) | CRHR1MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL10167449 | 0.75 | ALDH1A1 (0.38) | MAPTLMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL10167447 | 0.74 | ALDH1A1 (0.40) | MAPTLMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL10167434 | 0.74 | ALDH1A1 (0.37) | MAPTLMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL10167462 | 0.74 | TP53 (0.38) | MAPTLMNAKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | BASF SE (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | BASF SE (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | BASF SE (DE) | 2009-03-12 | — | — | US | disclosed |
| EP-1954138-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007057407-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057407-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | AAAS, API5, ATL3 | CRHR1 3974/4885MAPT 2683/4885LMNA 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.