Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139962 | 1.00 | PRKCA (0.61) | PRKCAMMP12ACACBACACANR1I2 | |
| SCHEMBL4146448 | 1.00 | PRKCA (0.61) | PRKCAMMP12ACACBACACANR1I2 | |
| SCHEMBL4146452 | 1.00 | PRKCA (0.61) | PRKCAMMP12ACACBACACANR1I2 | |
| Trifluoroacetic Acid SCHEMBL3092631 | 0.87 | PRKCA (0.72) | PRKCAMMP12ACACBACACANR1I2 | |
| Trifluoroacetic Acid SCHEMBL3093777 | 0.87 | PRKCA (0.72) | PRKCAMMP12ACACBACACANR1I2 | |
| SCHEMBL4153228 | 0.85 | PRKCA (0.64) | PRKCAMMP12NR1I2PDE5A | |
| SCHEMBL14110744 | 0.82 | PRKCA (0.67) | PRKCAMMP12NR1I2 | |
| SCHEMBL4152593 | 0.81 | PRKCA (0.55) | PRKCAMMP12NR1I2PDE5A | |
| Hydrochloric Acid SCHEMBL394699 | 0.81 | PRKCA (0.66) | PRKCAMMP12NR1I2 | |
| SCHEMBL14110783 | 0.79 | PRKCA (0.65) | PRKCAMMP12NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | PRKCA 4320/4885MMP12 3563/4885ACACB 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.