Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467164 | 0.86 | ALDH1A1 (0.69) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL11009450 | 0.86 | ALDH1A1 (0.69) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL6879275 | 0.83 | NPSR1 (0.63) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| Phenol SCHEMBL6873017 | 0.82 | ALDH1A1 (0.65) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL11014144 | 0.81 | MAPT (0.60) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL4147375 | 0.81 | CYP1A2 (0.51) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL31148410 | 0.79 | MEN1 (0.61) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL3278294 | 0.79 | MEN1 (0.61) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL6880252 | 0.78 | ALDH1A1 (0.60) | ALDH1A1NPSR1KMT2ALMNAMAPK1 | |
| SCHEMBL13696640 | 0.78 | ALDH1A1 (0.60) | ALDH1A1NPSR1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227587-A1 | Pyrimidines as inhibitors of phosphoinositide-3-kinases (PI3K) | WARNER-LAMBERT COMPANY LLC | 2009-09-10 | — | — | US | disclosed |
| EP-1682532-B1 | PYRIMIDINES AS INHIBITORS OF PHOSPHOINOSITIDE-3-KINASES (PI3K) | WARNER LAMBERT CO (US) | 2007-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227587-A1 | Pyrimidines as inhibitors of phosphoinositide-3-kinases (PI3K) | PIK3CA, PIK3CD, PIK3R5 | ALDH1A1 2412/4885NPSR1 3742/4885KMT2A 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.