SCHEMBL4140773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4136204	1.00	CHEK1 (0.45)	CHEK1TDO2IDO1CYP11B1CYP11B2
	SCHEMBL4144766	0.86	KDR (0.47)	CHEK1CDK1CDK4CCNA2CCND1
	SCHEMBL4145365	0.85	TTK (0.45)	CHEK1CDK1CDK4CCNA2CCND1
	SCHEMBL4149528	0.82	CHEK1 (0.50)	CHEK1GRM4CDK1CDK4CCNA2
	SCHEMBL4142185	0.81	NTSR1 (0.47)	CHEK1TDO2IDO1CYP11B1CYP11B2
	SCHEMBL4142181	0.81	NTSR1 (0.47)	CHEK1TDO2IDO1CYP11B1CYP11B2
	SCHEMBL4139812	0.81	KDM4E (0.38)	CHEK1GRM4PTGS1MEN1KMT2A
	SCHEMBL5922432	0.79	CHEK1 (0.53)	CHEK1TDO2CYP11B1CYP11B2GRM4
	SCHEMBL5922428	0.79	CHEK1 (0.53)	CHEK1TDO2CYP11B1CYP11B2GRM4
	SCHEMBL4153389	0.78	CHEK1 (0.53)	CHEK1TDO2IDO1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.