Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746207 | 1.00 | ALDH1A1 (0.53) | ALDH1A1PTPN5GAAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL8947519 | 0.98 | ALDH1A1 (0.52) | ALDH1A1PTPN5GAAMAPTKDM4E | |
| SCHEMBL964964 | 0.88 | GAA (0.50) | ALDH1A1PTPN5GAAMAPTTSHR | |
| SCHEMBL21603365 | 0.84 | CA1 (0.47) | ALDH1A1PTPN5GAAMAPTTSHR | |
| SCHEMBL29778868 | 0.84 | CA1 (0.47) | ALDH1A1PTPN5GAAMAPTTSHR | |
| SCHEMBL27202379 | 0.83 | ALDH1A1 (0.57) | ALDH1A1PTPN5GAAMAPTKDM4E | |
| SCHEMBL2429565 | 0.80 | POLB (0.41) | ALDH1A1PTPN5GAAMAPTTSHR | |
| SCHEMBL9217763 | 0.80 | ALDH1A1 (0.43) | ALDH1A1PTPN5GAAMAPTKDM4E | |
| SCHEMBL442808 | 0.79 | ALDH1A1 (0.50) | ALDH1A1PTPN5GAAMAPTKDM4E | |
| SCHEMBL2429802 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PTPN5GAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702646-B | Fluorenyl-biphenyl type epoxy material with high insulating property and preparation method thereof | 合肥工业大学 | 2024-05-31 | — | — | CN | claimed |
| CN-114702646-A | Fluorenyl-biphenyl epoxy material with high insulating property and preparation method thereof | 合肥工业大学 | 2022-07-05 | — | — | CN | claimed |
| CN-103073598-A | Synthesis of mononuclear (polynuclear) complex of Schiff's base and bismuth | LI QIANGGUO | 2013-05-01 | — | — | CN | claimed |
| US-20260092063-A1 | FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF | JAZZ PHARMACEUTICALS IRELAND LTD (IE) | 2026-04-02 | — | — | US | disclosed |
| US-12304912-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2025-05-20 | — | — | US | disclosed |
| CN-119264063-A | Preparation method of phenazine compound | 新乡医学院 | 2025-01-07 | — | — | CN | disclosed |
| CN-114702646-B | Fluorenyl-biphenyl type epoxy material with high insulating property and preparation method thereof | 合肥工业大学 | 2024-05-31 | — | — | CN | disclosed |
| US-20240124452-A1 | FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL TRUSTEE | 2024-04-18 | — | — | US | disclosed |
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11858930-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-01-02 | — | — | US | disclosed |
| US-11858930-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-01-02 | — | — | US | disclosed |
| EP-0667861-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994011350-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011349-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011351-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| EP-0596358-A1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1994-05-11 | — | — | EP | disclosed |
| WO-1994000124-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | WEBER ECKARD (US) | 1994-01-06 | — | — | WO | disclosed |
| EP-0493650-A1 | Fluorinated acetylene-containing aromatic amines and diamines | National Starch and Chemical Investment Holding Corporation (US) | 1992-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12304912-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | BRAF, RAF1, NRAS | ALDH1A1 2065/4885PTPN5 1725/4885GAA 3792/4885 |
| US-11858930-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | BRAF, RAF1, NRAS | ALDH1A1 2065/4885PTPN5 1725/4885GAA 3792/4885 |
| US-20240124452-A1 | FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF | BRAF, RAF1, NRAS | ALDH1A1 2065/4885PTPN5 1725/4885GAA 3792/4885 |
| US-20260092063-A1 | FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF | BRAF, NRAS, RAF1 | ALDH1A1 2381/4885PTPN5 444/4885GAA 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.