Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.48 |
| ▸ | USP2 | O75604 | 7/20 | 0.48 |
| ▸ | CASP1 | P29466 | 5/20 | 0.48 |
| ▸ | CASP7 | P55210 | 4/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845428 | 0.88 | USP2 (0.44) | ALDH1A1CYP1A2HSD17B10USP2CASP1 | |
| SCHEMBL4767494 | 0.86 | TSHR (0.47) | ALDH1A1CYP1A2USP2LMNAPOLB | |
| SCHEMBL1849473 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP1A2HSD17B10USP2CASP1 | |
| SCHEMBL1921365 | 0.86 | ALDH1A1 (0.40) | ALDH1A1CYP1A2HSD17B10USP2CASP1 | |
| SCHEMBL1846180 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP1A2HSD17B10USP2CASP1 | |
| SCHEMBL1923248 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HSD17B10USP2CASP1 | |
| SCHEMBL1921107 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HSD17B10USP2CASP1 | |
| SCHEMBL8898023 | 0.80 | HTT (0.64) | ALDH1A1HSD17B10USP2CASP1LMNA | |
| Maleic Acid SCHEMBL29413890 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1HSD17B10USP2CASP1LMNA | |
| Maleic Acid SCHEMBL2874748 | 0.78 | HSD17B10 (0.41) | ALDH1A1CYP1A2HSD17B10USP2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302000-A1 | COMBINATION DRUG TREATMENT TO INCREASE NEUROGENESIS FOR NEUROLOGICAL DISORDERS | Progenicyte Therapeutics, Inc. (US) | 2023-09-28 | — | — | US | disclosed |
| US-20210046079-A1 | COMBINATION THERAPY TO IMPROVE BRAIN FUNCTION OR PROMOTE NEUROGENESIS FOR TREATING NEURODEGENERATIVE CONDITIONS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2021-02-18 | — | — | US | disclosed |
| US-20090087462-A1 | Use of pyrimidine derivatives for cosmetic purposes | TREMBLEY MARCELLA | 2009-04-02 | — | — | US | disclosed |
| EP-1890673-A1 | USE OF PYRIMIDINE DERIVATIVES FOR COSMETIC PURPOSES | DSMIP Assets B.V. (NL) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133876-A1 | USE OF PYRIMIDINE DERIVATIVES FOR COSMETIC PURPOSES | DSM IP ASSETS B.V. (NL) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210046079-A1 | COMBINATION THERAPY TO IMPROVE BRAIN FUNCTION OR PROMOTE NEUROGENESIS FOR TREATING NEURODEGENERATIVE CONDITIONS | PSEN1, PSEN2, NES | ALDH1A1 4397/4885CYP1A2 4466/4885HSD17B10 873/4885 |
| US-20090087462-A1 | Use of pyrimidine derivatives for cosmetic purposes | TYMP, TYMS, UNG | ALDH1A1 1067/4885CYP1A2 1110/4885HSD17B10 2785/4885 |
| US-20230302000-A1 | COMBINATION DRUG TREATMENT TO INCREASE NEUROGENESIS FOR NEUROLOGICAL DISORDERS | NES, PSEN1, PSEN2 | ALDH1A1 2409/4885CYP1A2 4390/4885HSD17B10 4301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.